antigenic variation


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antigenic variation

successive changes in the surface ANTIGENS of certain MICROORGANISMS, resulting in a range of antigenically different forms. This can help a PATHOGEN, such as influenza virus, to avoid the host's immune defence system. See IMMUNITY.
References in periodicals archive ?
falciparum might have a key role in antigenic variation.
Nevertheless, evidence has been found that different RIFINs are being expressed on different parasite lines indicating that rif genes might have an additional role in antigenic variation and in immune evasion as well (26).
Antigenic variation and immune evasion in Plasmodium falciparum malaria, Immunol Cell Biol.
Barbour ACt Antigenic variation of a relapsing fever Borrelia species.
Barbour ACt Borrelia species and antigenic variation.
The ability of these spirochetes to undergo antigenic variation is well documented (25).
Extreme Intrasubtypic Antigenic Variation and the Pseudopandemic of 1947 (H1N1)
Influenza: epidemic patterns and antigenic variation.
Antigenic variation between CTFV strains is low, especially between strains from humans (21).
Of concem when these methods are used for characterizing these spirochetes is the organisms' ability to undergo multiphasic antigenic variation, which can be associated with large inter- or intraplasmidic recombinations/duplications (7,8).
Differences in glycosylation have been shown to contribute to antigenic variation by preventing antibody binding to antigenic sites (15).