modulation (redirected from antigenic modulation)

modulation /mod·u·la·tion/ (mod?u-la´shun)

1. the act of tempering.

2. the normal capacity of cell adaptability to its environment.

3. embryologic induction in a specific region.

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antigenic modulation  the alteration of antigenic determinants in a living cell surface membrane following interaction with antibody.

biochemical modulation  in combination chemotherapy, the use of a substance to modulate the negative side effects of the primary agent, increasing its effectiveness or allowing a higher dose to be used.

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mod·u·la·tion (mj-lshn)

n.

1. The functional and morphological fluctuation of cells in response to changing environmental conditions.

2. The variation of a property in an electromagnetic wave or signal, such as amplitude, frequency, or phase.

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modulation

the capacity to regulate; widely used in biology, e.g. modulation of immune responses, food intake, etc.

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antigenic modulation

the alteration of antigenic determinants in a living cell surface membrane following interaction with an antibody.

covalent modulation

activation or inactivation of enzymes, either by phosphorylation/dephosphorylation or by proteolytic cleavage. A major means of regulation of enzyme action by hormones.