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antigenic determinant

   Also found in: Dictionary/thesaurus, Legal, Encyclopedia, Wikipedia, Hutchinson 0.04 sec.
determinant /de·ter·mi·nant/ (de-ter´mĭ-nent) a factor that establishes the nature of an entity or event.
antigenic determinant  the structural component of an antigen molecule responsible for its specific interaction with antibody molecules elicited by the same or related antigen.
hidden determinant  an antigenic determinant in an unexposed region of a molecule so that it is prevented from interacting with receptors on lymphocytes, or with antibody molecules, and is unable to induce an immune response; it may appear following stereochemical alterations of molecular structure.

antigenic determinant
n.
Epitope.

antigenic determinant,
a site on an antigen molecule to which an antibody molecule binds. Also called epitope.

determinant
a factor that establishes or changes the nature of an entity or event. The factor may be environmental, be a part of the host or its defenses, be single or multiple and be immediate or remote.

allotypic determinant
an antigenic determinant which varies among members of the same species.
antigenic determinant
a structural component of an antigen against which immune responses are made and to which antibody or T cell receptor binds; an antigen such as a protein has many antigenic determinants. Called also epitope.
disease d's
factors which affect the occurrence or rate of ocurrence of a disease.
hidden determinant
an antigenic determinant located in an unexposed region of a molecule so that it is prevented from interacting with receptors on lymphocytes, or with antibody molecules, and is unable to induce an immune response; it may appear following stereochemical alterations of molecular structure.
isotypic determinant
one that occurs in all individuals of the same species.


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The second are relatively unique sequences such as virulence factor genes and antigenic determinant genes (27,28), which are used for species or serotype identification.
Identification of an antigenic determinant on the $2 domain of the severe acute respiratory syndrome coronavirus spike glycoprotein capable of inducing neutralizing antibodies.
Our phylogenetic data were based on analysis of the HMPV F protein, one of two viral glycoproteins considered the major antigenic determinant in RSV (11).
 
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