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site
(redirected from antigen-binding site)

   Also found in: Dictionary/thesaurus, Legal, Financial, Encyclopedia, Wikipedia 0.01 sec.
site (sīt) a place, position, or locus.
allosteric site  a site on a multi-subunit enzyme that is not the substrate binding site but that when reversibly bound by an effector induces a conformational change in the enzyme, altering its catalytic properties.
antigen-binding site , antigen-combining site the region of the antibody molecule that binds to antigens.
binding site  in an enzyme or other protein, the three-dimensional configuration of specific groups on specific amino acids that binds specific compounds, such as substrates or effectors, with high affinity and specificity.
operator site  a site adjacent to the structural genes in the operon, where repressor molecules are bound, thereby inhibiting the transcription of the genes in the adjacent operon.
restriction site  a base sequence in a DNA segment recognized by a particular restriction endonuclease.

site (st)
n.
A place; a location.
v.
To locate or situate at a site.

site
Etymology: L, situs, location
1 location. See also situs.
2 a quantum of space occupied and defined by a cluster of people.


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The antigen-binding site is formed where a heavy chain variable domain (VH) and a light chain variable domain (VL) come close together.
2], and Fab'), investigators now have an expanding repertoire of antibody forms with variable numbers of antigen-binding sites and with different molecular sizes and shapes.
The three-dimensional structure of HLA-B27 has a unique stereospecific antigen-binding site.
 
 
 
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