antifungal agent


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antifungal agent

see ANTIMICROBIAL AGENT.

antifungal agent 

Any substance which destroys or prevents the growth of fungi. It is one of the antibiotic groups. There are several classes of antifungal drugs: Polyenes, which cause an increase in fungal cell wall permeability leading to its death. Examples: amphotericin B, natamycin, nystatin. Azoles, which act either by inhibiting the synthesis of ergosterol, a component of fungal cell wall or by causing direct wall damage. Examples: clotrimazole, econazole, fluconazole, itraconazole, ketoconazole, miconazole. Pyrimidines, which interfere with the normal function of fungal cells. Example: flucytosine. Syn antimycotic agent.
References in periodicals archive ?
A randomized trial to assess once-daily topical treatment of tinea corporis with butenafine, a new antifungal agent.
Our study favours the use of antifungal agents after a positive culture report which is shown in multivariate analysis.
albicans as well as Candida non-albicans species against antifungal agents and may affect the prostaglandin production as well.
A number of in vitro and in vivo studies have been carried out by incorporating antifungal agents into denture lining materials and were shown to be more effective and preventive against denture stomatitis.
Triazole antifungal agents inhibit the fungal p450 enzyme 14 alpha-demethylase, which, in turn, blocks conversion of lanosterol to ergosterol and ultimately inhibits the essential production of ergosterol in fungal cell membranes.
Our study has again proved that regular aural suction toilet along with topical broad spectrum antifungal agent like clotrimazole is very effective in treatment of otomycosis.
The increased use of antifungal agents may have contributed to the development of highly resistant microorganisms or those which are more prone to develop resistance to drugs such fluconazole.
50] Antifungal agent ([micro]g/mL) ([micro]g/mL) U.
The widespread use of these antifungal agents have been followed by an increase in antifungal resistance and by a noticeable shift toward non albicans species with relative resistance to fluconazole and itraconazole [11] and there have been reports of emergence of resistance to antifungal agents in HIV/AIDS patients with OPC [12].
Merck, an international developer, manufacturer and distributor of pharmaceuticals, has received priority review status for a new drug application regarding investigational intravenous solution formulation of its antifungal agent, Noxafil (posaconazole) from the US Food and Drug Administration, according to reports yesterday.
M2 EQUITYBITES-August 7, 2013-Actavis Inc buys worldwide rights to Albaconazole antifungal agent from Palau Pharma(C)2013 M2 COMMUNICATIONS http://www.
M2 PHARMA-August 7, 2013-Actavis Inc buys worldwide rights to Albaconazole antifungal agent from Palau Pharma(C)2013 M2 COMMUNICATIONS