antifreeze

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antifreeze

A fluid with a high concentration of ethylene glycol or methanol, which is added to car, truck and other cooling systems for internal combustion engines to substantially reduce the freezing point of the coolant.

Antifreeze has long had currency as a surrogate inebriant despite it being associated with acidosis and renal shutdown (due to ethylene glycol), as well as blindness (due to methanol).

Clinical findings
In low amounts, antifreeze simulates alcohol metabolism; at high levels, it is associated with nausea, vomiting, seizures, coma or death (at levels above 100 ml of ethylene glycol).

antifreeze

Toxicology A fluid with a high concentration of ethylene glycol or methanol, which is added to car, truck, and other cooling systems for internal combustion engines to substantially ↓ the freezing point of the coolant; antifreeze has long had currency as a surrogate inebriant, despite its being associated with acidosis and renal shutdown–ethylene glycol and blindness–methanol Clinical In low amounts, antifreeze simulates alcohol metabolism; at high levels, it is associated with N&V, seizures, coma, death, at levels above 100 ml of ethylene glycol. See Leukovorin rescue. Methotrexatre

antifreeze

see ethylene glycol.
References in periodicals archive ?
Based on industry-wide practices, the other additives include, but are not limited to: sodium silicate, disodium phosphate, sodium molybdate, sodium borate, dextrin (hydroxyethyl starch), and a green dye, disodium fluorescein (dyes are added to antifreeze to help trace the source of leaks, and as an identifier because the different formulations are incompatible).
The characteristic odor in the automotive antifreeze formulation is caused by the tolytriazole.
The latter hypothesis needs to be confirmed with further study, as does the result indicating the improved performance of the antifreeze without the automotive components.
Effect of propylene glycol antifreeze on captures of Mexican fruit flies (Diptera: Tephritidae) in traps baited with biolures and AFF lures.
LOW TOX PROPYLENE GLYCOL ANTIFREEZE AS THE CAPTURE LIQUID.
The adsorption of antifreeze glycoproteins on an ice surface, says biochemist Robert E.
The researchers differ, however, over how firmly the antifreeze proteins bond to ice surfaces.
DeVries and his colleagues, for example, have looked at the way ice crystals in an antifreeze glycopeptide solution scatter light.
No one yet knows exactly how antifreeze molecules bind to an ice crystal.
Another question concerns the shape of these antifreeze glycopeptides in solution.
When ice does grow, it begins to grow abnormally," says Feeney, who has been working with Hallett and several colleagues and students to document the effects of antifreeze proteins on ice crystal structure.