antifolate chemotherapy

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Antifolate therapy Oncology The use of an antimetabolite–eg, MTX, to compete with folate, inhibiting dihydrofolate reductase, the enzyme responsible for → inactive dihydrofolate into an active tetrahydrofolate; this block causes a buildup of toxic dihydrofolate, shutting down synthesis of purine nucleotides and thymidylate; AC is used to treat malignancy. See Leukovorin rescue. Methotrexatre

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chemotherapy			antieczematic antielectron antiembolism hose antiemetic antiendotoxic antiendotoxin antienzyme antienzyme agent antiepileptic antiepileptic drugs antiestrogen antiestrogenic antiextractable nuclear antigens test antifebrile antifebrin antifertility antifibrillatory antifibrinolysin antifibrinolytic antifibrinolytics antifibrotic antifilarial antiflatulent antiflux antifoaming antifolate chemotherapy antifolate drug antifoulant antifreeze antifungal antifungal agent antifungal agents Antifungal Drugs, Systemic Antifungal Drugs, Topical antigalactic Antigas Agents Antigastroesophageal Reflux Drugs antigen antigen excess antigen presentation antigen processing antigen unit antigen-antibody glomerulonephritis antigen-antibody reaction antigen-presenting cell antigenemia antigenic antigenic determinant antigenic drift antigenic load antigenic shift			antifertility agent antifertilizin antifibrillatory antifibrinolysin antifibrinolysin antifibrinolytic antifibrinolytics antifibrotic antifilarial antifix antiflatulent antiflatulent Antiflood Valve antiflooding interceptor Antifluatulent Antifluatulent Antifluatulent antifluoridationist antiflux Antifoam (900) antifoaming Antifoaming agent antifoaming inhalant antifoaming inhalant antifoaming inhalant antifogging compound antifolate antifolate antifolate antifolate antifolate chemotherapy antifolate drug Antiform Antiform antifoulant antifouling antifouling coating antifouling paint antifreeze antifreeze antifreeze Antifreeze (coolant) Antifreeze (coolant) Antifreeze (coolant) Antifreeze (engine) Antifreeze (engine) Antifreeze (engine) Antifreeze activity Antifreeze Glycoproteins Antifreeze mixture Antifreeze mixture Antifreeze mixture Antifreeze protein Antifreeze proteins antifreeze sprinkler system Antifreeze, Batteries, Oil and Paint antifreezes antifreezes antifreezes Antifriction Antifriction

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