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antifibrotic

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antifibrotic /an·ti·fi·brot·ic/ (-fi-brot´ik) causing regression of fibrosis, or an agent that so acts.


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In the course of screening antifibrotic activity of natural products employing HSC-T6, a rat hepatic stellate cell line as an in vitro assay system, the methanolic extract of aerial parts of Eclipta prostrata L.
12) Subsequently, large controlled studies utilizing agents such as [gamma]-interferon-1b, (13) N-acetylcysteine (14) and the antifibrotic agent pirfenidone (15) failed to show clear benefit.
Pirfenidone is an oral agent undergoing clinical investigation in NF1, where its antifibrotic properties are used to target the fibrotic component of plexiform neurofibromas.
 
 
 
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