antifibrinolytics

antifibrinolytics

Drugs used to treat excessive bleeding as in menorrhagia or to help in the control of bleeding during surgery. Examples are tranexamic acid (Cyklokapron) and aprotinin (Trasylol).

antifibrinolytics (an´tēfī´brənolit´iks),

n a type of substance that prevents the breakdown of fibrin in blood clots. Used to prevent excessive bleeding.
References in periodicals archive ?
We next present a review of blood loss management strategies and antifibrinolytics in orthopaedic surgery.
Because of the complex nature of cancer care, collaboration with the adolescent's oncologist is highly recommended," according to the opinion, which outlines options for prophylactic menstrual suppression (combined hormonal contraceptives, progestin-only therapy, and gonadotropin-releasing hormone agonists) and emergent treatment of acute uterine bleeding (hormonal therapy, antifibrinolytics, and surgical options for patients who fail medical therapy).
Antifibrinolytics in liver transplantation: they are effective, but what about the risk-benefit ratio?
Medical treatments including hormones, antifibrinolytics, and iron salts are useful in the management of patients without gynecological pathology regardless of the etiology.
EPO, antifibrinolytics and cell salvage may have a greater potential role in CVR and FOA patients.
With the advent of field-deployable thromboelastography, it may also become possible to administer freeze-dried platelets, targeted procoagulants, such as recombinant Factor VIIa or activated prothrombin complex, or antifibrinolytics such as tranexemic acid.
New evidence shows that the use of antifibrinolytics in patients with traumatic bleeding offers a quick, inexpensive intervention to save lives from hemorrhage and conserve precious blood products.
6) Known side effects of the antifibrinolytics include nausea, diarrhea, vertigo, muscle cramps, postural hypotension, and fatigue.
Long-term prophylaxis includes use of androgens and antifibrinolytics, as well as the avoidance of known triggers.
Preoperative autologous blood donation, erythropoietin, cell salvage, hypotensive anesthesia, normovolemic hemodilution, and antifibrinolytics have all been tried with varying degrees of success.
The lack of use of autologous transfusion, cell salvage and antifibrinolytics may limit the applicability of our findings.