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antifibrinolysin |
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antifibrinolysin /an·ti·fi·bri·nol·y·sin/ (-fi″brĭ-nol´ĭ-sin) antiplasmin.
antiplasmin [an″te-, an″ti-plaz´min] a substance in the blood that inhibits plasmin. The most important is α2-antiplasmin, which acts by forming stable complexes with free plasmin. It is also crosslinked to fibrin by coagulation factor XIII and inhibits the binding of plasminogen to fibrin. Inherited deficiency of α2-antiplasmin results in tendency to severe bleeding, including extravasation into joints or their synovial cavities.
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