anticonvulsant

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anticonvulsant

 [an″te, an″ti-kon-vul´sant]
1. inhibiting convulsions.
2. an agent that has this effect, such as diphenylhydantoin (Dilantin), mephenytoin (Mesantoin), and trimethadione. They are used in the treatment of epilepsy and in psychomotor and myoclonic seizures.

an·ti·con·vul·sant

(an'tē-kon-vŭl'sant),
1. Preventing or arresting seizures.
2. An agent having such action.

anticonvulsant

/an·ti·con·vul·sant/ (-kon-vul´sant) inhibiting convulsions, or an agent that does this.

anticonvulsant

(ăn′tē-kən-vŭl′sənt, ăn′tī-)
n.
A drug that prevents or relieves convulsions.

an′ti·con·vul′sive (-sĭv) adj.

anticonvulsant

[-kənvul′sənt/]
Etymology: Gk, anti + L, convellere, to shake
1 pertaining to a substance or procedure that prevents or reduces the severity of epileptic or other convulsive seizures.
2 an anticonvulsant drug. Hydantoin derivatives, especially phenytoin, apparently exert their anticonvulsant effect by stabilizing the plasma membrane and decreasing intracellular sodium levels; as a result, the excitability of the epileptogenic focus is reduced. Phenytoin prevents the spread of excessive discharges in motor areas and suppresses arrhythmias originating in the thalamus, frontal lobes, and other brain areas. Succinic acid derivatives, valproic acid, and various barbiturates are among the drugs prescribed to limit or prevent absence seizures. Some benzodiazepines are also useful as anticonvulsants. Many of these agents can produce fetal malformations when administered to pregnant women. Also called antiepileptic.

anticonvulsant

adjective Related to preventing seizures noun Any agent used to prevent, reduce or stop seizures or convulsions. See Epilepsy.

an·ti·con·vul·sant

(an'tē-kŏn-vŭl'sănt)
1.Preventing or arresting seizures.
2. An agent having such action.

anticonvulsant

A drug used to prevent or reduce the severity of epileptic attacks, or to prevent dangerous muscle contraction in electroconvulsive therapy. Anticonvulsant drugs include PHENYTOIN (Epanutin), PHENOBARBITONE (phenobarbital) (Luminal), ETHOSUXIMIDE (Zarontin), CARBAMAZEPINE (Tegretol), SODIUM VALPROATE (Epilim) and CLONAZEPAM (Rivotril).

Anticonvulsant

A type of drug given to prevent seizures. Some patients with migraines can be treated effectively with an anticonvulsant.
Mentioned in: Antimigraine Drugs

an·ti·con·vul·sant

(an'tē-kŏn-vŭl'sănt)
1. Preventing or arresting seizures.
2. An agent having such action.
Synonym(s): anticonvulsive.

anticonvulsant

1. inhibiting convulsions. Any drug that depresses the central nervous system may be used for its anticonvulsant effect. This includes narcotics and sedatives. They have the undesirable effect of depressing all CNS functions.
2. a specific motor depressant, such as anticonvulsant or antiepileptic, which depresses specifically the motor centers and suppresses spontaneous motor activity; examples are phenobarbital, phenytoin, primidone and diazepam.
References in periodicals archive ?
Despite the boost in longevity that the anticonvulsant drugs yielded in worms, Kornfeld cautions that a similar effect has not been documented in people.
Serum and plasma for total and free anticonvulsant drug analyses: effects on EMIT assays and ultrafiltration devices.
5-fold more likely to be on treatment with an anticonvulsant drug than were controls, a statistically significant difference, reported Dr.
Carl Bazil, director of clinical anticonvulsant drug trials, Columbia University, New York.
Although nearly half the kids received lithium or an anticonvulsant drug to quell manic symptoms, their bipolar condition subsided no more often than that of their unmedicated peers.
In-depth analysis of the current and future anticonvulsant drug class market across the US, Japan, France, Germany, Italy, Spain and the UK.
We believe that the combination of strong evidence in the scientific literature of Ganaxolone's efficacy in epilepsy and our new proprietary formulation makes Ganaxolone a solidly viable anticonvulsant drug candidate.
The risks to the fetus from anticonvulsant drug use occurs very early in the pregnancy and is compounded by the fact that nearly 50 percent of pregnancies in the United States are unplanned, leaving women unaware and unprepared for the potential risks.
Abbott's MULTIGENT(TM) digoxin assay monitors levels of an anti-arrhythmic drug used in patients with heart problems, while Abbott's MULTIGENT valproic acid assay checks for levels of a commonly used anticonvulsant drug.
14 /PRNewswire/ -- A report from a research team headed by the director of the Harvard-based Antiepileptic Drug (AED) Pregnancy Registry details for the first time the risk of birth defects in women taking a widely used anticonvulsant drug.
26 /PRNewswire/ -- Portland Veterans Affairs Medical Center researchers and their colleagues have found that combining the anticonvulsant drug divalproex with either of two commonly used antipsychotic drugs significantly enhanced and hastened responses in patients suffering from acute psychotic episodes of schizophrenia.
Borges' project aims to engineer novel, safe and effective therapies for long-term treatment of epilepsies by providing the platform for the development of a delivery system capable of administering new and old anticonvulsant drugs.