anticonvulsant


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Related to anticonvulsant: Anticonvulsant Drugs

anticonvulsant

 [an″te, an″ti-kon-vul´sant]
1. inhibiting convulsions.
2. an agent that has this effect, such as diphenylhydantoin (Dilantin), mephenytoin (Mesantoin), and trimethadione. They are used in the treatment of epilepsy and in psychomotor and myoclonic seizures.

an·ti·con·vul·sant

(an'tē-kon-vŭl'sant),
1. Preventing or arresting seizures.
2. An agent having such action.

anticonvulsant

/an·ti·con·vul·sant/ (-kon-vul´sant) inhibiting convulsions, or an agent that does this.

anticonvulsant

(ăn′tē-kən-vŭl′sənt, ăn′tī-)
n.
A drug that prevents or relieves convulsions.

an′ti·con·vul′sive (-sĭv) adj.

anticonvulsant

[-kənvul′sənt/]
Etymology: Gk, anti + L, convellere, to shake
1 pertaining to a substance or procedure that prevents or reduces the severity of epileptic or other convulsive seizures.
2 an anticonvulsant drug. Hydantoin derivatives, especially phenytoin, apparently exert their anticonvulsant effect by stabilizing the plasma membrane and decreasing intracellular sodium levels; as a result, the excitability of the epileptogenic focus is reduced. Phenytoin prevents the spread of excessive discharges in motor areas and suppresses arrhythmias originating in the thalamus, frontal lobes, and other brain areas. Succinic acid derivatives, valproic acid, and various barbiturates are among the drugs prescribed to limit or prevent absence seizures. Some benzodiazepines are also useful as anticonvulsants. Many of these agents can produce fetal malformations when administered to pregnant women. Also called antiepileptic.

anticonvulsant

adjective Related to preventing seizures noun Any agent used to prevent, reduce or stop seizures or convulsions. See Epilepsy.

an·ti·con·vul·sant

(an'tē-kŏn-vŭl'sănt)
1.Preventing or arresting seizures.
2. An agent having such action.

anticonvulsant

A drug used to prevent or reduce the severity of epileptic attacks, or to prevent dangerous muscle contraction in electroconvulsive therapy. Anticonvulsant drugs include PHENYTOIN (Epanutin), PHENOBARBITONE (phenobarbital) (Luminal), ETHOSUXIMIDE (Zarontin), CARBAMAZEPINE (Tegretol), SODIUM VALPROATE (Epilim) and CLONAZEPAM (Rivotril).

Anticonvulsant

A type of drug given to prevent seizures. Some patients with migraines can be treated effectively with an anticonvulsant.
Mentioned in: Antimigraine Drugs

an·ti·con·vul·sant

(an'tē-kŏn-vŭl'sănt)
1. Preventing or arresting seizures.
2. An agent having such action.
Synonym(s): anticonvulsive.

anticonvulsant

1. inhibiting convulsions. Any drug that depresses the central nervous system may be used for its anticonvulsant effect. This includes narcotics and sedatives. They have the undesirable effect of depressing all CNS functions.
2. a specific motor depressant, such as anticonvulsant or antiepileptic, which depresses specifically the motor centers and suppresses spontaneous motor activity; examples are phenobarbital, phenytoin, primidone and diazepam.
References in periodicals archive ?
Bardai and his associates hypothesized that many of these deaths might be triggered by anticonvulsant drugs, especially those that block sodium channels such as carba-mazepine, lamotrigine, and phenytoin.
Previous pharmacological study with Cymbopogon citratus has demonstrated the occurrence of CNS effects and anticonvulsant properties (Blanco et al.
Watch for anticonvulsant-related adverse events in patients with hepatic insufficiency because hepatitis might hinder anticonvulsant metabolism.
Prolongation of the duration of seizure latency was taken as an index of protection indicating the anticonvulsant activity of the test compound.
Conclusion: Carbamazepine intoxication ranked first among the intoxications due to anticonvulsant exposures.
The essential oil exerted anticonvulsant activity in a dose-dependent manner in the present study.
If nimodipine in preventing tonic convulsions caused by PTZ [5], Aminophyline [1] and pilocarpine [10] have a protective effect, but unlike the above models in all tests anticonvulsant effect has been observed.
But anticonvulsants are known to block calcium channels in nerve cells, and Bao's group speculates that the drug helps protect neuronal connections between hair cells and auditory neurons.
Comparative double blind clinical trial of phenytoin and sodium valproate as anticonvulsant prophylaxis after craniotomy: efficacy, tolerability, and cognitive effects.
More recently, anticonvulsant medications have assumed a greater role in the pharmacologic management of SUD maintenance-phase treatment, At one time, these agents were routinely prescribed for withdrawal states associated with a high risk of seizures, but more recently have been used to impact cognitive, behavioral, and symptomatic dimensions of SUDs.
The link between anticonvulsant agents and suicidal acts or violent death--first revealed in a Food and Drug Administration meta-analysis in 2008--appears to have been confirmed for four of the drugs: gabapentin, lamotrigine, oxcarbazepine, and tiagabine, according to a new report.
In addition, the anticonvulsant agents were used as adjunctive treatment in many of the studies included in the meta-analysis, "further complicating the assessment of their individual effect.