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/an·ti·co·ag·u·la·tion/ (-ko-ag″u-la´shun)
1. the prevention of coagulation.
2. the use of drugs to render the blood sufficiently incoagulable to discourage thrombosis.


(ant″i-kō-ag″yŭ-lā′shŏn) [ anti- + coagulation]
The prevention or hindering of the coagulation of blood, esp. by an anticoagulant drug. anticoagulate (-kō-ag′yŭ-lāt″)

prophylactic anticoagulation

The administration of anticoagulant drugs to patients who have a high risk for venous thromboembolism, e.g., patients admitted to medical wards of hospitals or undergoing certain forms of surgery, esp. on the hips or knees.


The practice reduces the likelihood of the formation of blood clots but increases the risk of bleeding.
References in periodicals archive ?
The American College of Chest Physicians recommends 3 months of anticoagulation therapy for patients with VTE secondary to surgery or a transient, nonsurgical risk factor, and extended (possibly indefinite) anticoagulation for patients with unprovoked VTE or VTE caused by cancer.
While anticoagulation remains the overall gold standard in treating venous thromboembolism, IVC filters are a safe and effective means of PE prevention, and warrant consideration in patients who have a contraindication, failure or complication from anticoagulation.
There is a perception that elderly patients do not do well on anticoagulation.
When anticoagulation is required immediately, full anticoagulant doses of unfractionated heparin (UH) or low molecular weight heparin (LMWH) should be given concomitantly until 4 days after a therapeutic INR is reached.
Based on our rankings of risk-adjusted anticoagulation control at 100 VA sites (Rose et al.
Addition of acetylsalicylic acid to heparin for anticoagulation management during pumpless extracorporeal lung assist.
Directed by a board-certified cardiologist, and staffed by a nurse practitioner and specially trained nurses, the anticoagulation clinic team works with patients and their physicians to monitor and adjust their medication dosage.
1, the observed INR difference between Innovin and Neoplastin Plus is plotted against the mean of the INR values measured with the 2 thromboplastins for both patients on stable oral anticoagulant therapy and patients on unstable oral anticoagulation (including the patients initiating oral anticoagulation).
The author should be commended for preparing a case study for a difficult anticoagulation scenario, but must be careful in suggesting treatment and laboratory testing methods that are not necessarily proven.
This study provides valuable information that the placement of filters is of little value in patients who have no contraindication to the use of anticoagulation.

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