anticardiolipin antibody

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Related to anticardiolipin antibody: Antiphospholipid antibody, Lupus anticoagulant, anticardiolipin antibody syndrome

anticardiolipin antibody

Clinical immunology Any of a family of antibodies that recognize an epitope on the cardiolipin molecule; ACA are associated with immune-mediated disease, strokes, fetal wastage, syphilis, but are also found in healthy subjects without disease, represent natural antibodies, and indicate a normally functioning immune system Normal values IgA < 22 APL–IgA Phospholipid Units–PLU; IgG < 22 GPL–IgG PLUs; IgM < 11 MPL–IgM PLUs. See Antiphospholipid syndrome.

anticardiolipin antibody

Abbreviation: aCLa
An autoantibody against the cell membrane lipid, diphosphatidyl glycerol. It produces abnormal and sometimes life-threatening blood clotting. The antibody is found in a variety of autoimmune and infectious diseases, including in patients with the antiphospholipid antibody syndrome and syphilis.
See also: antibody

Patient discussion about anticardiolipin antibody

Q. what is anh cardiolipin antibody

A. Cardiolipin is a protein that is very common in the body. Mostly on heart and skeletal muscles. During several illnesses, mostly autoimmune, our body creates an antibody against it that do great damage and needs to cbe controlled.

More discussions about anticardiolipin antibody
References in periodicals archive ?
An international consensus statement on classification criteria for APS proposed two criteria: the presence of persistently moderate to high titer immunoglobulin G (IgG) or immunoglobulin M (IgM) anticardiolipin antibody (aCL) or lupus anticoagulant (LA) and the clinical complications of vascular thrombosis or pregnancy morbidity (1) (Table 1).
12) Our patient with anticardiolipin antibody syndrome had a prolonged activated partial thromboplastin time.
Anticardiolipin antibody (ACA) tests are among the most difficult of all ELISAs to standardize.
Variability of anticardiolipin antibody isotype distribution in 3 geographic populations of patients with systemic lupus erythematosus.
Anti-annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody.
Evaluation of the anticardiolipin antibody test: report of an international workshop held 4 April 1986.