antibody-instructive model

antibody-instructive model

a hypothetical explanation for antibody formation. It postulates that each antigenic contact in the life of an individual causes a new antibody to develop, as when a B cell comes in contact with an antigen and subsequently produces plasma cells and memory cells. The model maintains that the random contact of B cells with antigens induces the reticuloendothelial system to instruct memory cells to produce antibodies against antigens at any time. This model is not supported by experimental evidence. Compare antibody-specific theory.
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