ADEPT

(redirected from antibody-directed enzyme prodrug therapy)
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ADEPT

Cardiology
Advanced Elements of Pacing Trial. A trial comparing dual chamber pacemakers without rate response (DDD) and dual chamber pacemakers with rate response (DDDR).
 
Conclusion
An implantable cardioverter-defibrillator (ICD) that aggressively modulates heart rate (e.g., with DDDR pacing) does not improve exercise capacity or quality of life compared with non-aggressive pacing (e.g., DDD). Atrial fibrillation is more common with mode switching (MS) on; hospitalisation for CHF is more common with MS off.
 
Oncology
Antibody-directed enzyme prodrug therapy. A treatment protocol intended to decrease therapeutic cytotoxicity of certain drugs by administering an inactive prodrug and a monoclonal antibody that carries the prodrug’s activating enzyme to the target site.
 
Psychology
Adolescent Depression Prevention and Treatment. A study funded by the National Institute of Mental Health, examining the cost-effectiveness of a “service” model for treating children of depressed adults enrolled in health maintenance organisations (HMOs).

ADEPT

Psychology A study–Adolescent Depression Prevention & Treatment–funded by the Natl Inst Mental Health, examining the cost-effectiveness of a 'service' model for treating children of depressed adults enrolled in HMOs. See Depression.
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