antibiotic spacer

antibiotic spacer

A term for a mouldable material which is placed in the cavity following removal of an infected hip or knee joint prosthesis. Once the infection has been cleared, a revision arthroplasty is performed.
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Biau et al described a case of distal femur bone loss stabilised with intramedullary nail and antibiotic spacer followed by secondary grafting and eventual healing.
During the perioperative period with an antibiotic spacer, ESR and CRP values often times do not return to absolute normal values; on a case by case basis, aspiration of the affected joint after the same antibiotic holiday period will assist the surgeon in completing their assessment of infection eradication.
9) The Orthopaedic Research Society published a strong consensus statement that there was "No conclusive evidence to support mandatory joint aspiration prior to implant reimplantation" as well as "the option of a joint aspiration to be performed before reimplantation, when an antibiotic spacer is present, should be left to the discretion of the surgeon who can assess the complete clinical picture of their patient.
The efficacy was additionally demonstrated with successful implementation in cases of polymicrobial PJIs primarily treated with other antibiotic spacer options.
The patient was treated with intravenous (IV) vancomycin and was taken to the operating room for the left knee prosthesis removal and insertion of antibiotic spacer.
Once the canal has been adequately debrided, a long stem implant or antibiotic spacer is placed.
In Figure 7, the implant and all cement has been removed through a vascularized humeral door followed by insertion of an antibiotic spacer.
Caption: Figure 7 Grashey view of an antibiotic spacer in same patient after all the cement and prosthesis has been removed through a vascularized humeral door.
10) A second washout with reinsertion of an antibiotic spacer may be needed if the IL-6 remains high over a long period of time.
25) Many patients have shown improved functional results with the use of an antibiotic spacer as the definitive treatment.
In the two-stage revisions, custom-made antibiotic spacers loaded with vancomycin were used for 2 to 4 months.
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