antiarrhythmic


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antiarrhythmic

 [an″te-ah-rith´mik]
1. preventing or alleviating cardiac arrhythmias.
2. an agent that has this effect.

an·ti·ar·rhyth·mic

(an'tē-ă-ridh'mik),
Combating an arrhythmia.
Synonym(s): antidysrhythmic

antiarrhythmic

/an·ti·ar·rhyth·mic/ (-ah-rith´mik)
1. preventing or alleviating cardiac arrhythmias.
2. an agent that so acts.

antiarrhythmic

(ăn′tē-ə-rĭth′mĭk, ăn′tī-)
adj.
Preventing or alleviating irregularities in the force or rhythm of the heart.
n.
An antiarrhythmic drug.

antiarrhythmic

[-ərith′mik]
Etymology: Gk, anti + rhythmos, rhythm
1 pertaining to a procedure or substance that prevents, alleviates, or corrects an abnormal cardiac rhythm.
2 an antiarrhythmic agent. A defibrillator that delivers a precordial electric shock is often used to restore a normal rhythm to rapid, irregular atrial or ventricular contractions. A pacemaker may be implanted in a patient with an extremely slow heart rate or another arrhythmia. The electrode catheter of an external pacemaker may be threaded through a vein to the heart in cases of ventricular standstill or complete heart block. The major antiarrhythmic drugs are lidocaine hydrochloride, and a combination of disopyramide phosphate, procainamide hydrochloride, and quinidine. The antiadrenergic blocking agent propranolol hydrochloride may be used in treating arrhythmias. Isoproterenol hydrochloride is indicated for complete heart block and ventricular arrhythmias requiring an increased force of cardiac contractions to establish a normal rhythm. Atropine may be used in the treatment of bradycardia, a sedative in the treatment of tachycardia, and digitalis in the treatment of atrial fibrillation. Calcium channel blockers control arrhythmias by inhibiting calcium ion influx across the plasma membrane of cardiac muscle, thus slowing atrioventricular conduction and prolonging the effective refractory period within the AV node. See also arrhythmia.

antiarrhythmic

adjective Referring to an agent or mechanism that counters cardiac arrhythmias noun An agent that prevents or ameliorates cardiac arrhythmias

antiarrhythmic

1. preventing or alleviating cardiac arrhythmias.
2. an agent that prevents or alleviates cardiac arrhythmias.

antiarrhythmic drugs
include quinidine, procainamide, lidocaine, beta-adrenergic blockers such as propranolol, autonomic drugs including atropine and epinephrine, and digitalis.
References in periodicals archive ?
The major findings of the present study are: (1) matrine possessed the anti-arrhythmic effect induced by ouabain in guinea pigs; (2) the ionic targets of the antiarrhythmic effect of matrine were [I.
Previous studies have shown that ablation of atrial fibrillation results in about a 66% relative risk reduction in recurrence, but most focused on patients with AF refractory to one or more antiarrhythmic drugs, Dr.
Proarrhythmia with class III antiarrhythmic drugs: types, risks, and management.
The plaintiffs accused the doctor in charge of negligence, noting that the physician failed to perform an electrocardiogram, which the suit said was required for antiarrhythmic treatment.
Multaq's primary challenge will be its modest antiarrhythmic efficacy compared with that of its main competitor, amiodarone (Sanofi-Aventis's Cordarone, generics)," said Decision Resources Analyst Matthew Killeen, Ph.
The results are "vastly superior" to antiarrhythmic drug therapy in terms of maintenance of sinus rhythm, improvement in quality of life, and reduction of symptoms.
These are reliable in assessment of the function of the sinus node, anterograde atrioventricular conduction, refractory period of atria, and atrioventricular accessory connections, which can provoke and terminate tachycardia, and the efficacy of antiarrhythmic drugs.
The final chapter of the handbook lists the side effects, dosing, and clinical trial results for class I, II, III, and IV antiarrhythmic drugs.
However, [beta]-blockers have also been linked to growth retardation when prescribed as antiarrhythmic agents in normotensive pregnant women.
Negative opinions of antiarrhythmic Multaq have emerged among physicians following the black box warning given by the US FDA on December 19, 2011, noting that the drug must be not prescribed for people with a history of heart failure.
The market will also be driven by sales of the antiarrhythmic agent dronedarone (Sanofi-Aventis's Multaq), which will take share from class IC and class III antiarrhythmics to capture 11 percent of the total atrial fibrillation patient share in 2018.
ORLANDO -- The novel multi-channel-blocking antiarrhythmic agent dronedarone cut the risk of cardiovascular hospitalization or all-cause mortality by 24% in a meta-analysis of five placebo-controlled, randomized trials involving 6,157 patients with atrial fibrillation or atrial flutter.