antiandrogen /an·ti·an·dro·gen/ (-an´dro-jen) any substance capable of inhibiting the biological effects of androgens.
Antiandrogen
androgen [an´dro-jen]
antiandrogen
an·ti·an·dro·gen ( n t -n dr -jn, nt -)n. A substance that prevents expression of biological effects of androgenic hormones on responsive tissues. |
Antiandrogen
A substance that blocks the action of androgens, the hormones responsible for male characteristics. Used to treat prostate cancers that require male hormones for growth.
Mentioned in: Prostate Cancer
androgen [an´dro-jen]
any steroid hormone that promotes male secondary sex characters. The two main androgens are androsterone and testosterone. Called also androgenic hormone. adj., adj androgen´ic.
The androgenic hormones are internal endocrine secretions circulating in the bloodstream and manufactured mainly by the testes under stimulation from the pituitary gland. To a lesser extent, androgens are produced by the adrenal glands in both sexes, as well as by the ovaries in women. Thus women normally have a small percentage of male hormones, in the same way that men's bodies contain some female sex hormones, the estrogens. Male secondary sex characters include growth of the beard and deepening of the voice at puberty. Androgens also stimulate the growth of muscle and bones throughout the body and thus account in part for the greater strength and size of men as compared to women.
The androgenic hormones are internal endocrine secretions circulating in the bloodstream and manufactured mainly by the testes under stimulation from the pituitary gland. To a lesser extent, androgens are produced by the adrenal glands in both sexes, as well as by the ovaries in women. Thus women normally have a small percentage of male hormones, in the same way that men's bodies contain some female sex hormones, the estrogens. Male secondary sex characters include growth of the beard and deepening of the voice at puberty. Androgens also stimulate the growth of muscle and bones throughout the body and thus account in part for the greater strength and size of men as compared to women.
androgen insensitivity syndrome complete androgen resistance.
antiandrogen
any substance capable of inhibiting the biological effects of androgenic hormones.
antiandrogen
Endocrinology A hormone or other agent–eg, megestrol acetate, spironolactone, flutamide, nilutamide, and cimetidine, which interferes with androgen function by competitively inhibiting androgen binding to cognate receptors
at the target organ and is either biologically inert or functionally very weak; these compounds are used to manage androgen-dependent CAs–♂ breast and prostate, hirsutism, acne
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