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anti-sperm antibody

   Also found in: Acronyms 0.01 sec.
anti-sperm antibody
Any of a group of antibodies produced against 4 distinct components of the sperm; although ASAs are linked to infertility, their presence is not associated with a particular disease; ASAs may be found in the circulation, either free or as immune complexes, in seminal fluid and/or attached to the sperm surface Ref range/normal IgA, IgG, IgM < 15% binding


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In one study, 64% of 66 couples without significant sperm surface anti-sperm antibody had adequate sperm motility in cervical mucus, compared with only 26% of 122 couples where sperm-associated anti-sperm antibodies were detected.
Epicyte has five antibody products in development in its core areas of infectious disease and sexual health, including products to protect against the transmission of Herpes Simplex Virus 1 and 2 and HIV and an anti-sperm antibody to prevent conception.
These include an anti-herpes antibody to protect against the transmission of Herpes Simplex Virus 1 and 2 and an anti-sperm antibody to prevent conception.
 
 
 
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