anti-oestrogenic

anti-oestrogenic

adjective Referring to an effect that suppresses or inhibits oestrogenic activity.
 
noun An agent that counters oestrogenic activity.
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References in periodicals archive ?
Tamoxifen is a long acting anti-oestrogen with both oestrogenic and anti-oestrogenic effects.
14) When endogenous oestrogens are high, the weak oestrogenic nature of soy isoflavones results in anti-oestrogenic responses.
Some patients (20%-28%) do not respond to clomiphene citrate in spite of high dose as the anti-oestrogenic effect is dose-dependent; a daily dose of clomiphene citrategreater than 150mg is not recommended.
Most of the phytooestrogens-based preparations freely available on the market are proposed as legal and non-toxic anti-oestrogenic compounds (to counterbalance the side effects of anabolic steroids, mainly based on methoxyflafones (Usui, 2006)), as fat lowering products or sexual enhancing compounds based mainly on plant extracts from Commiphora Mukul (Guggulsterone), Eurycoma Longifolia (methoxyflavone), Vitex Agnus Castus and Astragalus Root (isoflavones).
Tamoxifen exerts tissue-dependent oestrogenic and anti-oestrogenic actions after binding to the ER [20].
Special emphasis has been placed on the mechanism of action of the aromatase inhibitor compared to that of clomiphene citrate, since the aromatase inhibitor lacks an anti-oestrogenic effect on the endometrium and cervical mucus.
Where concentrations of endogenous oestrogens are relatively high, as in premenopausal women, they can exclude the more potent oestrogen from binding to the receptor and, therefore, the overall effect is anti-oestrogenic.
A recent Oxford University study found smokers take, on average, around two months longer to conceive because ciggies produce anti-oestrogenic chemicals which can affect egg quality and even suppress ovulation.
Phyto-oestrogens have both oestrogenic and anti-oestrogenic effects and they're a drop in the ocean compared to the oestrogens your own body is making.
The centre, which is based at the Welsh School of Pharmacy at Cardiff University, is trying to identify the complex mechanisms that the cancer cells use to become resistant to these anti-oestrogenic drugs.
It exhibits anti-oestrogenic activity in the breast and oestrogen-like actions on the endometrium.