anti-oestrogenic

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anti-oestrogenic

adjective Referring to an effect that suppresses or inhibits oestrogenic activity.
 
noun An agent that counters oestrogenic activity.
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References in periodicals archive ?
They pointed mostly to preclinical data in arguing that tamoxifen's mixed estrogenic and anti-estrogenic effects could spell trouble in the form of an increase in breast cancer with longer-term use.
There is increasing evidence that estrogen is protective against heart disease and heart attacks, and smoking is definitely anti-estrogenic," he said.
These findings are seeding doubts about the wisdom of administering the potent anti-estrogenic drug for years -- perhaps for life -- to healthy women.
PCBs can act as endocrine-disrupting agents that presumably exert deleterious effects on the gonads and the reproductive tract because of their estrogenic and/or anti-estrogenic activity (Kholkute et al.
Pisha E, Pezzuto JM (1997) Cell-based assay for the determination of estrogenic and anti-estrogenic activities.
Because the jury is still out on whether soy is anti-estrogenic or estrogenic, I suggest no more than a single serving of soy a day.
Recombinant cell bioassays for endocrine disruptors: development of a stably transfected human ovarian cell line for the detection of estrogenic and anti-estrogenic chemicals.
A nonsteroidal anti-estrogenic agent for women with ductal carcinoma in situ (DCIS) following breast surgery and radiation therapy Nolvadex is indicated to reduce the risk of invasive breast cancer.
An oral anti-estrogenic drug, Fareston inhibits estrogen-induced stimulation of DNA synthesis and cellular replication.
They also provide a unique source of isoflavones -- anti-estrogenic compounds that inhibit the products of cancer genes, he notes.
Many breast cancer patients are prescribed tamoxifen as adjuvant therapy, but the anti-estrogenic effects of tamoxifen may not prevent pregnancy (Cancer Imaging 2008;8:135-45).
Seventy percent of breast cancers are estrogen receptor (ER)-positive, and are therefore presumed to be hormone-responsive and potentially treatable or preventable by anti-estrogenic agents.