anti-Ro

anti-Ro

A non-organ specific IgG (IMMUNOGLOBULIN G) autoantibody directed against a soluble ribonucleoprotein. It is associated with SJÖGREN'S SYNDROME and other connective tissue disorders. Maternal anti-Ro can reach the fetal heart via the placenta during pregnancy and cause damage to the conducting system, resulting in congenital heart block.
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