anti-IgE antibody

anti-IgE antibody

Allergy medicine An antibody directed against IgE. See Allergy.
References in periodicals archive ?
Studies using anti-IgE antibody in food allergy management are limited, but show promising results.
Currently available treatment using omalizumab (an anti-IgE antibody sold under the trade name Xolair) can block new interactions between IgE and FcR, but it is not designed to pry the molecules apart once they've formed a bond on the surface of a mast cell.
These results suggest that, after incubation with CAF, the anti-IgE antibody used in ELISA was unable to detect the IgE.
Likewise, the anti-IgE antibody omalizumab (Xolair(R); Genentech, Novartis) for the treatment of asthma can also be successfully converted into a BiTE antibody.
Omalizumab, an anti-IgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis.
It has been established that anti-IgE antibody induces passive cutaneous anaphylaxis (PCA) as a typical in vivo model for immediate hypersensitivity in anaphylactic reactions.
2003;167:1232-8), and the humanized monoclonal anti-IgE antibody omalizumab (Int.
A recombinant humanized monoclonal anti-IgE antibody, Xolair (omalizumab) can exert beneficial effects with a once- or twice-per-month administration.
The effect of treatment with omalizumab, an anti-IgE antibody, on asthma exacerbations and emergency medical visits in patients with severe persistent asthma.
For instance, a monoclonal anti-IgE antibody injection therapy now in clinical testing, called omalizumab, works by blocking IgE before it can bind to the mast cell, thus interrupting the trigger that releases inflammatory chemicals such as histamine, which causes allergy symptoms.
5 mL/L), the mouse monoclonal anti-IgE antibody DNA conjugate and its complementary circular DNA were applied to each array and incubated at 37 [degrees]C for 30 min.
The reported efficacy of the injectable anti-IgE antibody omalizumab (Xolair) has validated IgE as an important target for the treatment of allergic diseases.