anthracycline /an·thra·cy·cline/ (-si´klēn) a class of antineoplastic antibiotics produced by Streptomyces peucetius and S. coeruleorubidus, including daunomycin and doxorubicin. 
anthracycline [an″thrah-si´klēn]
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Anthracycline. For daunorubicin, R1=sbondCH3; for doxorubicin, R1=sbondCHOH.
anthracycline [an″thrah-si´klēn]
a class of antibiotics isolated from cultures of Streptomyces peucetius; it includes the antineoplastic agentsdaunorubicin and doxorubicin. The use of these drugs is limited by a chronic, cumulative, dose-related toxicity resulting in irreversible congestive heart failure.
Anthracycline. For daunorubicin, R1 = -CH3; for doxorubicin, R1 = -CHOH.
anthracycline
a class of antibiotics isolated from cultures of Streptomyces peucetius; it includes the antineoplastic agents daunomycin and doxorubicin. See also anthracycline antibiotic.
anthracycline
Oncology A chemotherapeutic used in leukemia to prevent cell division Adverse effects Dose-dependent stomatitis, N&V and BM suppression which 'maxes' at ± 10 days; alopecia is normal; extravasation at IV
injection site causes severe, protracted ulcers and necrosis. See Chemotherapy, Daunorubicin, Doxorubicin, Idarubicin.
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