anterior ischaemic optic neuropathy

neuropathy, anterior ischaemic optic (AION)

A group of disorders that have in common ischaemia of the anterior portion of the optic nerve (especially the optic nerve head). Affected patients, usually between 50 and 75 years of age, present with sudden, severe visual loss often accompanied by periocular pain and jaw claudication. The disc is pale and swollen and severe optic atrophy eventually ensues. Ischaemia is due either to inflammation of the arterioles (posterior ciliary arteries) supplying blood to the anterior portion of the optic nerve (i.e. arteritic) or to an idiopathic aetiology (i.e. non-arteritic). Arteritic AION generally affects older individuals and is most commonly associated with temporal (giant cell) arteritis. Systemic findings include weight loss, malaise, scalp and joint pain and tenderness, and possibly hypertension. Rapid diagnosis and treatment (usually corticosteroids) is crucial in order to avoid permanent visual loss as well as systemic complications. Non-arteritic AION generally affects younger patients and causes severe visual loss. There are few systemic effects of the condition. No specific treatment has been identified. See arteriosclerosis; altitudinal hemianopia.
References in periodicals archive ?
Optic nerve head swelling and haemorrhages are not a feature of PION and in this case these features could have been caused by raised intracranial pressure (due to the intracranial haemorrhage), the bleeding tendency associated with dengue infection and/or concomitant anterior ischaemic optic neuropathy (AION).
Unilateral conditions such as optic neuritis, anterior ischaemic optic neuropathy and central retinal vessel occlusions can cause an RAPD.
d) Left inferior altitudinal defect, commonly associated with anterior ischaemic optic neuropathy
The most common such syndrome is termed anterior ischaemic optic neuropathy (AION).
In non-arteritic anterior ischaemic optic neuropathy, which of these statements is true?

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