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anophthalmia

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anophthalmia /an·oph·thal·mia/ (an″of-thal´me-ah) a developmental anomaly characterized by complete absence of the eyes (rare) or by the presence of vestigial eyes.
an·oph·thal·mi·a (nf-thlm-, -p-)
n.
Complete absence of tissues of the eyes.

anophthalmia, anophthalmos
a developmental anomaly marked by complete absence of one or both eyes or the presence of rudimentary eyes. Occurs most commonly in pigs and sheep.

anophthalmia 
Congenital absence of all tissues of the eyes. It is due to a failure of the outgrowth of the optic vesicle to form the optic cup. However, in many cases some development occurs and there is a rudimentary presence of one or both eyes, such as extreme microphthalmia. Syn. anophthalmos; anophthalmus; anopia. See optic cup; microphthalmia; monophthalmia; optic vesicle.


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Early prenatal exposure results in anophthalmia, whereas late prenatal exposure results in folded retina (Acuff-Smith et al.
 
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