Key Words: Anonychia, Anonychia totalis, Complete anonychia, Congenital
Complete anonychia means absence of all nails of fingers and toes.
Her affected brother had two sons and one daughter with anonychia while two other daughters were phenotypically normal.
Keeping in view her history and physical examination, she was diagnosed to have simple congenital anonychia totalis with secondary complications.
Complete anonychia generally follows an autosomal recessive pattern and has been mapped to chromosome 20p135.
5,11,12) Altman, Perry, (13) Scott and Scott (14) reported nail changes occurring in 1-16% of the patients, whereas Scott and Scott (14) reported longitudinal ridging, grooving, splitting, striations, anonychia
, subungual hyperkeratosis and thinning.
4) Nail dysplasia is an essential feature of this syndrome manifested by the presence of triangular lunulae that can be accompanied by anonychia
, hemianonychia, nail hypoplasia, or longitudinal ridging.
congenita totalis: a case report and review of the literature.
He had bilateral and asymmetrical terminal deficiency of fingers, symbrachydactyly with anonychia of toes, and aplasia cutis congenita of the scalp.
KEY WORDS: Adams-Oliver syndrome, Transverse limb deficiency, Aplasia cutis congenita, Scalp defect, Symbrachydactyly, Anonychia, Pakistani subject.
Terminal transverse deficiency of fingers, symbrachydactyly with anonychia of toes, and congenital scalp defect: Case report of a subject with Adams-Oliver syndrome.
He also had generalized xerosis, hyperkeratosis over the palms and soles, minimal lichenification over knees and anonychia