ANXA1

(redirected from annexin-1)

ANXA1

A gene on chromosome 9q21.13 that encodes annexin 1, a calcium/phospholipid-binding protein that promotes membrane fusion and is involved in exocytosis. Annexin 1 regulates phospholipase A2 activity and thus may have anti-inflammatory activity.
References in periodicals archive ?
Annexin-1 downregulation is associated with clinical outcome in Chinese patients with hilar cholangiocarcinoma.
We previously demonstrated that Kirenol can upregulate nuclear Annexin-1, inhibit NE-KB activity in the synovium and reduce 1L-1 p.
Recently we demonstrated that Kirenol can upregulate the nuclear expression of Annexin-1 to inhibit NF-KB activity and reduce pro-inflammatory cytokine expression, and that Kirenol has no obvious effect on the hypothalamus-pituitary-adrenal axis in a rat CIA model (Wang et al.