anistreplase

(redirected from anisoylated plasminogen streptokinase activator complex)
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anistreplase

 [an″is-trep´lās]
a thrombolytic agent primarily used to clear coronary vessel occlusions associated with myocardial infarction; administered intravenously.

anistreplase

/an·is·trep·lase/ (an″is-trep´lās) a thrombolytic agent used to clear coronary vessel occlusions associated with myocardial infarction.

anistreplase

a plasminogen activator.
indication This drug is used in acute MI for lysis of coronary artery thrombi.
contraindications Known hypersensitivity to this drug or streptokinase; active internal bleeding; intraspinal or intracranial surgery; central nervous system neoplasms; severe, uncontrolled hypertension; cerebral embolism; thrombosis; hemorrhage; recent trauma; or history of cerebrovascular accident all prohibit the use of this drug.
adverse effects Adverse effects of this drug include headache, fever, sweating, agitation, dizziness, paresthesia, tremor, vertigo, hypotension, conduction disorders, nausea, vomiting, decreased hematocrit, surface bleeding, rash, urticaria, phlebitis at the injection site, itching, flushing, low back pain, arthralgia, altered respirations, and dyspnea. Life-threatening side effects include intracranial hemorrhage, dysrhythmias, GI bleeding, genitourinary bleeding, intracranial bleeding, retroperitoneal bleeding, thrombocytopenia, bronchospasm, lung edema, and anaphylaxis.

anistreplase

See APSAC.

anistreplase

A clot-dissolving drug used to try to re-establish blood flow in the heart muscle in the early treatment of heart attacks. A brand name is Eminase.