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anion gap

   Also found in: Dictionary/thesaurus, Financial, Acronyms, Encyclopedia, Wikipedia, Hutchinson 0.06 sec.
anion gap
n.
The difference between the sum of cations and anions found in plasma or serum.

anion gap
method used to evaluate a patient's acid-base status; based on the observation that the sum of blood cations (sodium, potassium, chloride and bicarbonate ions) usually exceeds the sum of the anions (sulfates, phosphates, proteinates, organic acid ions); the difference between the two is the anion gap. Significant departure from the normal level of difference indicates acid-base disturbance.

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3 mmol/L, chloride 99 mmol/L, and bicarbonate 14 mmol/L, with an anion gap of 17.
Lactic acidosis is characterized by elevated blood lactate levels (greater than 5 mmol/L), decreased pH, electrolyte disturbances with an increased anion gap, and an increased lactate/pyruvate ratio.
 
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