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angiotensinogen

   Also found in: Acronyms, Encyclopedia, Wikipedia 0.02 sec.
angiotensinogen /an·gio·ten·sin·o·gen/ (-ten-sin´o-jen) a serum α2-globulin secreted in the liver which, on hydrolysis by renin, gives rise to angiotensin.
an·gi·o·ten·sin·o·gen (nj--tn-sn-jn)
n.
A serum globulin formed by the liver that is cleaved by renin to form angiotensin I. Also called angiotensin precursor.

angiotensinogen
[-tensin′əjən]
a serum glycoprotein produced in the liver that is the precursor of angiotensin.

angiotensinogen
a serum α2-globulin secreted in the liver which, on hydrolysis by renin, gives rise to angiotensin.

angiotensinogen
Renin substrate A 60 kD glycoprotein of the α2 globulin fraction of plasma proteins, which is synthesized and released from the liver, and cleaved in the circulation to form the biologically inactive, angiotensin I, a decapeptide split from the N-terminal by renin, a proteolytic enzyme. See Angiotensin, Renin-angiotensin system.


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[17] A fall in blood pressure causes renin to be released from the kidneys, which catalyzes the conversion of angiotensinogen to angiotensin I.
and French researchers reported that a gene coding for a protein called angiotensinogen appeared to play a role in the regulation of blood pressure (SN: 10/10/92, p.
and French researchers targeted a gene that codes for a protein called angiotensinogen (AGT), an important raw material in the chemical process that regulates blood pressure.
 
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