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angiotensin-converting enzyme |
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angiotensin-converting enzyme /an·gio·ten·sin-con·vert·ing en·zyme/ (-ten´sin kon-vert´ing en´zim) see peptidyl-dipeptidase A.
angiotensin-converting enzyme (anˑ·jē·ō·ten·sin kon·verˑ·ting enˑ·zīm), n glycoprotein that converts angiotensin I to angiotensin II by dividing two terminal amino acids. angiotensin-converting enzyme A key enzyme in the RAA system, which converts the inactive decapeptide angiotensin I to the octapeptide, angiotensin II, a potent vasoconstrictor that also stimulates aldosterone secretion; ACE is also involved in metabolizing bradykinin Ref range 18–67 U/L, > age 20; those < 20 have higher levels; ACE is ↑ in sarcoidosis, Gaucher disease, leprosy, histoplasmosis, cirrhosis, asbestosis, berylliosis, DM, Hodgkin's disease, hyperthyroidism, amyloidosis, PBC, idiopathic pulmonary fibrosis, PE, scleroderma, silicosis, TB; ACE ↓ in response to prednisone therapy for sarcoidosis. See Renin/angiotensin/aldosterone system. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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? Mentioned in | ? References in periodicals archive | |
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The serum angiotensin-converting enzyme level is elevated in
75% of untreated patients with sarcoidosis. All other parameters,
including C-reactive protein levels, angiotensin-converting enzyme, and
tumor markers were normal. 2% of residents with congestive heart failure were not
receiving an angiotensin-converting enzyme inhibitor. |
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