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angiotensin II

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angiotensin II
n.
An octapeptide that is a potent vasopressor and a powerful stimulus for production and release of aldosterone from the adrenal cortex.

angiotensin II (anˈ·jē·ō·tenˑ·sin tōō),
n a powerful stimulant used to raise blood pressure by stimulating the release of aldosterone while concurrently causing vasoconstriction.


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It utilizes two complementary mechanisms of action, calcium channel blockade and angiotensin II receptor blockade.
Normally, ACE converts the compound angiotensin I into angiotensin II, which induces the blood vessels to constrict and blood pressure to rise.
1]R is one of the four G protein-coupled receptors that mediates intracellular signaling induced by angiotensin II (Touyz and Berry 2002).
 
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