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angiotensin I |
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angiotensin I An N-terminal decapeptide produced when renin acts on angiotensinogen; A-I is the precursor of angiotensin II, but itself has no known physiologic role. See Angiotensinogen. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Normally, ACE converts the compound angiotensin I into angiotensin II,
which induces the blood vessels to constrict and blood pressure to rise. [17] A
fall in blood pressure causes renin to be released from the kidneys,
which catalyzes the conversion of angiotensinogen to angiotensin I. Renin, a highly specific aspartyl protease, cleaves
angiotensinogen, to yield angiotensin I, which is further converted into
angiotensin II by ACE (Angiotensin Converting Enzyme). |
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