angiotensin I


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Related to angiotensin I: angiotensin II

an·gi·o·ten·sin I

(an'jē-ō-ten'sin),
A decapeptide of slightly variable sequence, depending on the animal source, formed from the tetradecapeptide angiotensinogen by the removal of four amino acid residues, a reaction catalyzed by renin; a peptidase cleaves off a dipeptide (histidylleucine) to yield angiotensin II, the physiologically active form.

angiotensin I

An N-terminal decapeptide produced when renin acts on angiotensinogen. Angiotensin I is the precursor of angiotensin II but itself has no known physiologic role.

angiotensin I

An N-terminal decapeptide produced when renin acts on angiotensinogen; A-I is the precursor of angiotensin II, but itself has no known physiologic role. See Angiotensinogen.

angiotensin I

is converted to angiotensin II by the action of renal renin, causing generalized vasoconstriction and increased blood pressure
References in periodicals archive ?
Angiotensin II (formed from angiotensin I in a reaction catalyzed by angiotensin converting enzyme (ACE, kininase II)), is a potent vasoconstrictor, the primary vasoactive hormone of the renin-angiotensin system and an important component in the pathophysiology of hypertension.
Further biological processing of angiotensin I produces angiotensin II, which directly elevates blood pressure.
ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II.
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