angiosarcoma


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an·gi·o·sar·co·ma

(an'jē-ō-sar-kō'mă),
A rare malignant neoplasm occurring most often in soft tissue; believed to originate from the endothelial cells of blood vessels; microscopically composed of spindle-shaped cells, some of which line small spaces resembling vascular clefts.

angiosarcoma

/an·gio·sar·co·ma/ (an″je-o-sahr-ko´mah) a malignant neoplasm arising from vascular endothelial cells; the term may be used generally or may denote a subtype, such as hemangiosarcoma.
hepatic angiosarcoma  a malignant liver tumor characterized by dilated sinusoids with hypertrophied or necrotic hepatocytes that leave vascular channels lined by malignant cells; it usually affects older men and has been linked to exposure to toxins.

angiosarcoma

(ăn′jē-ō-sär-kō′mə)
n.
A malignant tumor arising from vascular tissue.

angiosarcoma

[-särkō′mə]
a rare, malignant tumor consisting of endothelial and fibroblastic tissue that proliferates and eventually surrounds vascular channels. It begins in the lining of the blood vessels. The condition usually occurs in older persons. Angiosarcoma has been associated with exposure to many foreign materials in the body, such as steel, shrapnel, and plastic. This tumor tends to be aggressive and recurs locally as well as metastasizing. Also called hemangiosarcoma, malignant hemangioendothelioma. Compare angioma.
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Angiosarcoma

angiosarcoma

An uncommon, aggressive mesenchymal malignancy, arising in the skin, liver, breast, soft tissues and viscera, primarily affecting the elderly; male:female, 2:1.Aetiology Most are idiopathic; some are linked to chronic lymphoedema (as occurs following axillary dissection for breast CA), others to radiation therapy; hepatic angiosarcoma is classically linked exposure to thorium dioxide (a long obsolete contrast medium), and is also associated with arsenic and vinyl chloride. 
Prognosis Poor, 10–20% 5-year survival.

an·gi·o·sar·co·ma

(an'jē-ō-sahr-kō'mă)
A rare malignant neoplasm occurring most often in the breast and skin, and believed to originate from the endothelial and fibroblastic cells of blood vessels; microscopically composed of closely packed round or spindle-shaped cells, some of which line small spaces resembling vascular clefts.

angiosarcoma

A rare malignant tumour of the lining cells of small blood vessels that often occurs in several places at once and may affect the liver as a complication of CIRRHOSIS. It is known to occur in people who were exposed to the medical contrast medium thorotrast up to 25 years before and has been found in workers with vinyl chloride. The tumour is highly malignant and treatment is rarely effective.

angiosarcoma

a malignant tumor of vascular tissue. Called also hemangiosarcoma, lymphangiosarcoma.
References in periodicals archive ?
Diagnosing a cardiac angiosarcoma is typically challenging because of its rarity and because tumors originating from the upper right atrium are always covered by pulmonary tissue or fat pad, rendering them less detectable by transthoracic echocardiography.
MRI shows diffuse hyperintensity with variable ADC values which are higher than the mean seen in other hepatic malignancies, but low ADC values as compared to that seen in benign cysts and hemangiomas [7] The imaging feature of angiosarcoma with hepatocyte specific contrast, which has an additional advantage for scanning the patient at a delayed interval of 90 minutes is possible.
42) Epithelioid angiosarcoma is highly aggressive, often with early nodal and solid organ metastasis.
Definitive diagnosis of MAE is based on morphological and immunohistochemical findings that differentiate it from other vascular lesions of the spleen, including splenic hemangioma, lymphangioma, angiosarcoma, littoral cell angioma, hamartoma, and sclerosing angiomatoid nodular transformation (SANT) of the spleen.
The differential diagnosis of angiosarcoma includes haemangioma for the better differentiated lesions, Kaposi's sarcoma for those with a predominantly spindle component, and carcinoma or amelanotic melanoma for the poorly differentiated types.
We report a case of epithelioid angiosarcoma involving the urinary bladder and prostate in a patient with a history of external beam radiation for prostatic adenocarcinoma.
In high-grade cases, the differential diagnosis of epithelioid angiosarcoma should be excluded.
The histopathological examination showed an expansion by a relatively circumscribed, variable cellular proliferation of neoplastic spindled cells arranged in fascicles, a conventional high-grade angiosarcoma, with proliferating vascular channels that dissect dermal collagen and adipose tissue, with prominent tumor necrosis and epidermis ulceration (Figures 2-5).
However, despite the operation, " Raymond's angiosarcoma returnedand, in recent months, a hole began to develop under his right eye.
Studies have demonstrated that LCA has two subtypes with potentially malignant properties, littoral cell angiosarcoma (11) and littoral cell hemangioendothelioma.
Epithelioid angiosarcoma in a patient with Klippel-Trenaunay-Weber Syndrome: an unexpected response to therapy.
1 The term pseudoangiomatous was proposed due to the resemblance of PASH to low-grade angiosarcoma on low power examination.