angiosarcoma


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an·gi·o·sar·co·ma

(an'jē-ō-sar-kō'mă),
A rare malignant neoplasm occurring most often in soft tissue; believed to originate from the endothelial cells of blood vessels; microscopically composed of spindle-shaped cells, some of which line small spaces resembling vascular clefts.

angiosarcoma

/an·gio·sar·co·ma/ (an″je-o-sahr-ko´mah) a malignant neoplasm arising from vascular endothelial cells; the term may be used generally or may denote a subtype, such as hemangiosarcoma.
hepatic angiosarcoma  a malignant liver tumor characterized by dilated sinusoids with hypertrophied or necrotic hepatocytes that leave vascular channels lined by malignant cells; it usually affects older men and has been linked to exposure to toxins.

angiosarcoma

(ăn′jē-ō-sär-kō′mə)
n.
A malignant tumor arising from vascular tissue.

angiosarcoma

[-särkō′mə]
a rare, malignant tumor consisting of endothelial and fibroblastic tissue that proliferates and eventually surrounds vascular channels. It begins in the lining of the blood vessels. The condition usually occurs in older persons. Angiosarcoma has been associated with exposure to many foreign materials in the body, such as steel, shrapnel, and plastic. This tumor tends to be aggressive and recurs locally as well as metastasizing. Also called hemangiosarcoma, malignant hemangioendothelioma. Compare angioma.
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Angiosarcoma

angiosarcoma

An uncommon, aggressive mesenchymal malignancy, arising in the skin, liver, breast, soft tissues and viscera, primarily affecting the elderly; male:female, 2:1.Aetiology Most are idiopathic; some are linked to chronic lymphoedema (as occurs following axillary dissection for breast CA), others to radiation therapy; hepatic angiosarcoma is classically linked exposure to thorium dioxide (a long obsolete contrast medium), and is also associated with arsenic and vinyl chloride. 
Prognosis Poor, 10–20% 5-year survival.

an·gi·o·sar·co·ma

(an'jē-ō-sahr-kō'mă)
A rare malignant neoplasm occurring most often in the breast and skin, and believed to originate from the endothelial and fibroblastic cells of blood vessels; microscopically composed of closely packed round or spindle-shaped cells, some of which line small spaces resembling vascular clefts.

angiosarcoma

A rare malignant tumour of the lining cells of small blood vessels that often occurs in several places at once and may affect the liver as a complication of CIRRHOSIS. It is known to occur in people who were exposed to the medical contrast medium thorotrast up to 25 years before and has been found in workers with vinyl chloride. The tumour is highly malignant and treatment is rarely effective.

angiosarcoma

a malignant tumor of vascular tissue. Called also hemangiosarcoma, lymphangiosarcoma.
References in periodicals archive ?
Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas.
EHE of bone is a low-grade malignant vascular tumour with a relatively benign course in contrast to the poorly differentiated angiosarcoma.
Angiosarcoma associated with irradiation of the breast was first noted back in the 1940s, and in that report it was said to be associated with chronic lymphedema.
Twu NF, Juang C, Yeng S, Lu CI, Lai CZ, Chao KC (1999) Treatment of primary pure angiosarcoma of ovary with multiple lung metastases: A case report.
A review of the Angiosarcoma products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
The tumor cells were immunohistochemically reactive for Factor VIII, FLI-1, and CD34, consistent with hepatic angiosarcoma.
Epithelioid hemangioma of the penis: a clinicopathologic and immunohistochemical analysis of 19 cases, with special reference to exuberant examples often confused with epithelioid hemangioendothelioma and epithelioid angiosarcoma.
A patient with cardiac angiosarcoma who survived for four years.
Occupationally-related diseases associated with PVC production include angiosarcoma of the liver and lung disease.
Respectively, these are angiosarcoma, GI stromal tumor, lymphoma, metastatic adenocarcinoma, and granulomatous disease such as tuberculosis.
With regard to neoplastic causes, primary bone lymphoma, angiosarcoma, haemangioendothelioma, and spindle cell pseudotumours may appear similar to KS on radiographs.