angiomyolipoma


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angiomyolipoma

 [an″je-o-mi″o-lĭ-po´mah]
a benign tumor containing vascular, adipose, and muscle elements, occurring most often in the kidney with smooth muscle elements.

an·gi·o·my·o·li·po·ma

(an'jē-ō-mī'ō-li-pō'mă),
A benign neoplasm of adipose tissue (lipoma) in which muscle cells and vascular structures are fairly conspicuous; most commonly a renal tumor containing smooth muscle, often associated with tuberous sclerosis.
[angio- + G. mys, muscle, + lipos, fat, + -oma, tumor]

angiomyolipoma

/an·gio·myo·li·po·ma/ (-mi″o-lĭ-po´mah) a benign tumor containing vascular, adipose, and muscle elements, occurring most often as a renal tumor with smooth muscle elements (more correctly called angiolipoleiomyoma ), usually in association with tuberous sclerosis, and considered to be a hamartoma.

angiomyolipoma

(ăn′jē-ō-mī′ō-lĭ-pō′mə)
n.
A benign tumor composed of adipose tissue, muscle cells, and vascular structures.

angiomyolipoma

A benign, well-circumscribed, nonencapsulated tumour-like lesion or hamartoma (perivascular epithelioid cell tumour—PEComa), which is the most common mesenchymal lesion of the kidney. It is composed of blood vessels, smooth muscle and mature fat, and is typically seen in the kidney or paranephric tissue. Angiomyolipoma also occurs in the fallopian tube, liver, nasal cavity, penis, skin, spermatic cord and vagina, and can mimic renal cell carcinoma. Up to 50% of patients have tuberous sclerosis (TS); 75% of TS patients have angiomyolipomas.

Clinical findings
May cause catastrophic bleeds.
 
Molecular pathology
TSC1 and TSC2 mutations.

an·gi·o·my·o·li·po·ma

(an'jē-ō-mī'ō-li-pō'mă)
A benign neoplasm of adipose tissue (lipoma) in which muscle cells and vascular structures are fairly conspicuous.

angiomyolipoma

a benign tumor containing vascular, adipose and muscle elements, occurring most often in the kidney with smooth muscle elements.
References in periodicals archive ?
Cystic angiomyolipoma of the kidney: a clinicopathologic description of 11 cases.
1998) Criteria Age at Onset Major Facial angiofibroma Infancy to adulthood Ungual fibroma Adolescence to adulthood Shagreen patch Childhood Hypomelanotic macule Infancy to childhood Cortical tuber Fetal life Subependymal nodule Childhood to adolescence Subependymal giant Childhood to adolescence cell tumor Retinal hamartoma Infancy Cardiac rhabdomyoma Fetal life Renal angiomyolipoma Childhood to adulthood Lymphangioleiomyomatosis Adolescence to adulthood Minor Multiple pits in dental enamel Hamartomatous rectal polyps Bone cysts Cerebral white-matter radial migration lines Gingival fibromas Nonrenal hamartoma Retinal achromic patch "Confetti" skin lesions Multiple renal cysts Note.
Characterization of renal cell carcinoma, oncocytoma, and lipid-poor angiomyolipoma by unenhanced, nephrographic, and delayed phase contrast-enhanced computed tomography.
Angiomyolipomas (AMLs) belong to the broader group of neoplasms known as perivascular epithelioid cell tumors or PEComas.
Novartis received approval from the European Commission (EC) for VotubiaA (everolimus) tablets for the treatment of adult patients with renal angiomyolipoma associated with tuberous sclerosis complex (TSC) who are at risk of complications (based on factors such as tumor size or presence of aneurysm, or presence of multiple or bilateral tumors) but who do not require immediate surgery.
Various conditions such as sebaceous cyst, midline epidemoid cyst, angiomyolipoma , varicocele, hematoma, hamartomas of the scrotum could be confused with hemangioma.
Angiomyolipoma (AML) are benign tumours composed of varying amounts of thick-walled dysplastic blood vessels, smooth muscle and mature adipose tissue derived from epithelioid cells.
Background: Angiomyolipoma is an uncommon soft tissue tumor that is usually defined by triphasic features of mature adipose tissue, mixed thick-walled blood vessels, and benign smooth muscle and is confirmed with a melanocytic marker positivity.
These included neuroendocrine, non-small cell lung, angiomyolipoma, pancreatic, prostate, renal cell and testicular cancers.
The first impression of the radiologist was spontaneous rupture of renal cell carcinoma (RCC), and the second was fat depletion angiomyolipoma.