angioimmunoblastic lymphadenopathy with dysproteinemia


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Related to angioimmunoblastic lymphadenopathy with dysproteinemia: Angioimmunoblastic T-cell lymphoma

lymphadenopathy

 [lim-fad″ĕ-nop´ah-the]
disease of the lymph nodes; called also adenopathy.
angioimmunoblastic lymphadenopathy (angioimmunoblastic lymphadenopathy with dysproteinemia (AILD)) a systemic disorder resembling lymphoma characterized by fever, night sweats, weight loss, generalized lymphadenopathy, hepatosplenomegaly, macropapular rash, polyclonal hypergammaglobulinemia, and Coombs'-positive hemolytic anemia. It is considered to be a nonmalignant hyperimmune reaction to chronic antigenic stimulation; there is proliferation of B cells accompanied by profound deficiency of T cells. The disease follows a progressive but extremely variable course: some patients survive for a long period without chemotherapy; in other patients, overwhelming infections rapidly lead to death
dermatopathic lymphadenopathy regional lymph node enlargement associated with melanoderma and other dermatoses marked by chronic erythroderma.
immunoblastic lymphadenopathy angioimmunoblastic lymphadenopathy.
lymphadenopathy syndrome a condition occurring in immunocompromised individuals, characterized by unexplained lymphadenopathy for 3 or more months that involves extrainguinal sites, which on biopsy reveal nonspecific lymphoid hyperplasia. See also AIDS-related complex.

an·gi·o·im·mu·no·blas·tic lym·phad·e·nop·a·thy with dys·pro·tein·e·mi·a (AILD),

a lymphoproliferative disorder characterized by generalized lymphadenopathy, hepatosplenomegaly, fever, sweats, weight loss, skin lesions, and pruritus with hypergammaglobulinemia; occurs primarily in older adults, often with fatal outcome. Proliferation of B cells and deficiency of T cells have been demonstrated.

angioimmunoblastic lymphadenopathy with dysproteinemia (AILD)

a systemic disorder resembling lymphoma, characterized by fever, night sweats, weight loss, and generalized lymphadenopathy. There are cellular infiltration of lymphocytes, immunoblasts, and plasma cells; change or effacement of lymph node architecture; hepatosplenomegaly; maculopapular rash; polyclonal hypergammaglobulinemia; and Coombs' positive hemolytic anemia. It is considered to be a nonmalignant hyperimmune reaction to chronic antigenic stimulation. There are proliferation of B cells and profound deficiency of T cells. The disease follows a progressive but variable course; some patients have long survival without chemotherapy, whereas others have a rapid course, with death from overwhelming infection.

an·gi·o·im·mu·no·blas·tic lymph·ad·e·nop·a·thy with dys·pro·tein·e·mia

(an'jē-ō-im'yū-nō-blas'tik limf'ad-ĕ-nŏp'ă-thē dis'prō-tēn-ē'mē-ă)
A lymphoproliferative disorder characterized by generalized lymphadenopathy, hepatosplenomegaly, fever, sweats, weight loss, skin lesions, and pruritus withhypergammaglobulinemia; occurs primarily in older adults, often with fatal outcome. Proliferation of B cells and deficiency of T cells have been demonstrated.