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angioimmunoblastic lymphadenopathy with dysproteinemia |
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angioimmunoblastic lymphadenopathy with dysproteinemia (AILD), a systemic disorder resembling lymphoma, characterized by fever, night sweats, weight loss, and generalized lymphadenopathy. There are cellular infiltration of lymphocytes, immunoblasts, and plasma cells; change or effacement of lymph node architecture; hepatosplenomegaly; maculopapular rash; polyclonal hypergammaglobulinemia; and Coombs' positive hemolytic anemia. It is considered to be a nonmalignant hyperimmune reaction to chronic antigenic stimulation. There are proliferation of B cells and profound deficiency of T cells. The disease follows a progressive but variable course; some patients have long survival without chemotherapy, whereas others have a rapid course, with death from overwhelming infection. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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