angiogenin


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Related to angiogenin: VEGF

angiogenin

[an′jē·ōjen′in]
a protein that mediates the formation of blood vessels. A single-chain basic protein cloned from molecules of the tumor angiogenesis factor (TAF) in human colon cancer cells, angiogenin is used experimentally to stimulate the development of new blood vessels in wound healing, cerebrovascular accident, and coronary artery disease.

ANG

A gene on chromosome 14q11.1-q11.2 that encodes angiogenin, a potent mediator of angiogenesis, the structure of which is similar to pancreatic ribonuclease.
References in periodicals archive ?
It was concluded that high serum levels of VEGF, bFGF, angiogenin and endostatin were observed in patients with HCC.
While Vallee kept his work on angiogenin under wraps, other scientists have described other blood-vessel stimulating chemicals.
The ancillary activity confuses the issue," he says, adding that angiogenin is 1,000 times as potent in triggering blood vessel growth as is the fibroblast growth factor.
Valleehs major interest is not the therapeutic applications of angiogenin, but the basic question of how the growth and development of biological systems is turned on and off.
Angiogenin, a RNase involved in angiogenesis, has a similar tissue distribution (5).
For example, in addition to its angiogenic effects, angiogenin specifically degrades transfer RNA, but not messenger RNA (14).