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angiogenesis inhibitor

   Also found in: Dictionary/thesaurus, Wikipedia 0.06 sec.
angiogenesis inhibitor,
a group of drugs that prevent the growth of new blood vessels into a solid tumor.

angiogenesis inhibitor
Oncology A chemotherapy adjuvant which inhibits the angiogenesis required for tumor growth and survive, especially for metastastatic tumors See CAI, CM101, IFN-alpha, IL-12, Marimastat, Pentosan polysulfate, Platelet factor 4, Thalidomide, TNP-470.


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Folkman notes, however, that autopsies find small, previously undiscovered prostate tumors in nearly half of men over 50 who die of other causes, suggesting that some natural force - perhaps an angiogenesis inhibitor - has held the tumors in check.
"This is a very potent angiogenesis inhibitor," Folkman says.
The drug is an angiogenesis inhibitor, operating much like the drugs that have received widespread publicity in recent days, angiostatin and endostatin.
 
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