angiogenesis /an·gio·gen·e·sis/ (-jen´ĕ-sis) vasculogenesis; development of blood vessels either in the embryo or in the form of neovascularization or revascularization.
Angiogenesis
angiogenesis
angiogenesis [an″je-o-jen´ĕ-sis]
angiogenesis (anˈ·jē·ō·jeˑ·n
·sis),
angiogenesis
an·gi·o·gen·e·sis ( n j - -j n  -ss)n. The formation of new blood vessels, especially blood vessels that supply oxygen and nutrients to cancerous tissue. an gi·o·genic (-jnk) adj. |
Angiogenesis
The formation of new blood vessels, for example, as a result of a tumor.
Mentioned in: Antiangiogenic Therapy
angiogenesis
[an′jē·ōjen′əsis]
Etymology: Gk, angeion + genesis, origin
the formation of new blood vessels, a process controlled by chemicals produced in the body that stimulate blood vessels or form new ones. Angiogenesis plays an important role in the growth and spread of cancer. Angiogenesis also occurs in the healthy body for healing of wounds and restoring blood flow to tissues after injury.
angiogenesis [an″je-o-jen´ĕ-sis]
1. development of blood vessels in the embryo.
2. any formation of new blood vessels; see also neovascularization (def. 2) and revascularization. Called also angiopoiesis and vasculogenesis. adj., adj angiogenic.
tumor angiogenesis the induction of the growth of blood vessels from surrounding tissue into a tumor by a diffusible protein factor released by the tumor cells.
angiogenesis (anˈ·jē·ō·jeˑ·n
·sis),n the formation and growth of new blood vessels.
angiogenesis
the development of blood vessels.
tumor angiogenesis
the induction of the growth of blood vessels from surrounding tissue into a solid tumor by a diffusible chemical factor released by the tumor cells.
VEGF (vascular endothelial growth factor)
A major protein involved in regulating the differentiation and proliferation of vascular endothelial cells thus promoting the growth of new blood vessels (angiogenesis). VEGF is essential for normal embryonic development and contributes to the maintenance and repair of tissues. There are several VEGF proteins, depending on the number of amino acids that they contain (e.g. VEGF 121, VEGF 165, VEGF 189 and VEGF 206). However, under certain circumstances (e.g. higher than normal levels of VEGF as happens in hypoxia) it may participate in cancerous processes, inflammatory processes (e.g. rheumatoid arthritis) and ocular neovascularization as in exudative (wet) age-related macular degeneration and diabetic retinopathy. Anti-VEGF drugs are used to inhibit the action of VEGF. See anti-VEGF drugs.
angiogenesis
The sprouting of new blood vessels and capillary beds from existing vessels, which plays a fundamental role in embryonic development, tissue and wound repair, resolution of inflammation, and onset of neoplasia; angiogenesis is
linked to certain pathologies–eg, cancer, diabetic retinopathy, rheumatoid arthritis
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