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anaplasia |
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anaplasia /ana·pla·sia/ (-pla´zhah) dedifferentiation; loss of differentiation of cells and of their orientation to one another and to their axial framework and blood vessels, a characteristic of tumor tissue.anaplas´tic
anaplasia [an′əplā′zhə] Etymology: Gk, ana + plassein, to shape a change in the structure and orientation of cells, characterized by a loss of differentiation and reversion to a more primitive form. Anaplasia is characteristic of malignancy. Compare aplasia. anaplastic, adj. anaplasia (an´ n a regressive change in cells toward a more primitive or embryonic cell type. It is a prominent characteristic of malignancy in tumors. anaplasia loss of differentiation of cells, an irreversible alteration in adult cells toward more primitive (embryonic) cell types; a characteristic of tumor cells. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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(3) The tumor we describe belongs in this category, although our case is
unique in view of our distinguishing findings of the absence of fibrosis
and neuronal tissue and the presence of abundant gemistocytes, mild
vascular proliferation, perivascular cuffing, mild cellular anaplasia,
and mitoses. Fibromatosis
occupies an intermediary position, and microscopic sections contain
markedly cellular lesions of mature proliferative fibroblastic tissue,
with infrequent mitoses and occasional atypia, but no frank anaplasia. Nuclear anaplasia can be seen, but mitotic figures
are rare. |
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