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anaplasia

   Also found in: Dictionary/thesaurus, Wikipedia 0.09 sec.
anaplasia /ana·pla·sia/ (-pla´zhah) dedifferentiation; loss of differentiation of cells and of their orientation to one another and to their axial framework and blood vessels, a characteristic of tumor tissue.anaplas´tic
an·a·pla·sia (n-plzh)
n.
Reversion of cells to an immature or a less differentiated form, as occurs in most malignant tumors.

anaplasia
[an′əplā′zhə]
Etymology: Gk, ana + plassein, to shape
a change in the structure and orientation of cells, characterized by a loss of differentiation and reversion to a more primitive form. Anaplasia is characteristic of malignancy. Compare aplasia. anaplastic, adj.

anaplasia (an´plā´zh),
n a regressive change in cells toward a more primitive or embryonic cell type. It is a prominent characteristic of malignancy in tumors.

anaplasia
loss of differentiation of cells, an irreversible alteration in adult cells toward more primitive (embryonic) cell types; a characteristic of tumor cells.


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(3) The tumor we describe belongs in this category, although our case is unique in view of our distinguishing findings of the absence of fibrosis and neuronal tissue and the presence of abundant gemistocytes, mild vascular proliferation, perivascular cuffing, mild cellular anaplasia, and mitoses.
Fibromatosis occupies an intermediary position, and microscopic sections contain markedly cellular lesions of mature proliferative fibroblastic tissue, with infrequent mitoses and occasional atypia, but no frank anaplasia.
Nuclear anaplasia can be seen, but mitotic figures are rare.
 
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