anaemia of chronic disease
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anaemia of chronic diseaseA form of anaemia that accounts for 1/4 of all anaemias in hospitalised patients; it is the predominant form of hypoproliferative anaemia, which interferes with RBC production and shortens RBC lifespan, and is seen in patients with arthritis, chronic infections, and malignancy.
The findings in anaemia of chronic disease reflect the underlying aetiology.
Mild-to-moderate anaemia, often microcytic ± hypochromic; iron stores may be low/normal; RBC indices may be normal.
Unknown; possibly related to IFN-gamma produced by activated macrophages.