aplastic anaemia(redirected from anaemia gravis)
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aplastic anaemiaAnaemia due to a failure in marrow production of RBCs, often accompanied by failure in WBC and platelet production (i.e., granulocytopaenia, thrombocytopaenia).
Toxins (benzene, toluene, insecticides), radiotherapy, drugs (carbamazepine, chemotherapy, chloramphenicol, gold salts, phenytoin, phenylbutazone, quinacrine, sulfonamides, tolbutamide), autoimmunity, SLE, post-hepatitis, pregnancy, paroxysmal nocturnal haemoglobinuria.
Aplastic anaemia is often unresponsive to specific therapy.