anabolic steroid


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steroid

 [ster´oid]
any of a group of lipids with a complex molecule containing carbon atoms in four interlocking rings forming a hydrogenated cyclopentophenanthrene-ring system; three of the rings contain six carbon atoms each and the fourth contains five. Steroids are important in body chemistry and include steroid hormones such as the gonadal or sex steroids, corticosteroids, glucocorticoids, and mineralocorticoids; vitamins of the D group; and the sterols, including cholesterol, the main building block of the steroid hormones in the body. The cardiac glycosides, a group of compounds derived from certain plants, are partly steroids.
anabolic steroid any of a group of synthetic derivatives of testosterone having pronounced anabolic properties and relatively weak androgenic properties; they are used clinically mainly to promote growth and repair of body tissues in diseases or states promoting catabolism or tissue wasting.
gonadal steroid (sex steroid) a steroid hormone produced by a gonad, such as an androgen, estrogen, or progestational agent.

an·a·bol·ic ster·oid

a compound with androgenic properties that increases muscle mass and stimulated protein production; used to treat emaciation; sometimes used by athletes in an effort to increase size, strength, and endurance of muscle. Examples include methyltestosterone, nandrolone, methandrostenolone, and stanozolol.

anabolic steroid

n.
Any of a group of synthetic steroid hormones that promote the storage of protein and the growth of tissue, sometimes used by athletes to increase muscle size and strength. Nonprescription sale of anabolic steroids was declared illegal in the United States in 1990.

anabolic steroid

[an′əbol′ik]
Etymology: Gk, anaballein, to build up
any of several compounds derived from testosterone or prepared synthetically to promote general body growth, to oppose the effects of endogenous estrogen, or to promote masculinizing effects. All such compounds cause a mixed androgenic-anabolic effect.
indications It is prescribed in the treatment of aplastic anemia, red-cell aplasia, and hemolytic anemia and in anemias associated with renal failure, myeloid metaplasia, and leukemia.
contraindications It is contraindicated for the palliation of carcinoma of the breast; in pregnancy and serious cardiac, renal, and hepatic diseases; and with known hypersensitivity.
adverse effects Among the most serious adverse effects are acne, growth of facial hair, and hoarsening or deepening of the voice; other masculinizing features are common. Continued use of these compounds in women may also produce prominent musculature, hirsutism, and hypertrophy of the clitoris.

anabolic steroid

A drug or hormone-like substance chemically or pharmacologically related to 17-α-alkylated testosterone that promotes muscle growth, which are commonly abused by athletes. Lipid changes by ASs are more marked with oral stanazol (manufactured for horses) than with IV testosterone; it decreases HDL-C (especially HDL2) and increases hepatic TG lipase (HDL) catabolism.
 
Indications
Children, adolescents with delayed puberty, decreased growth, small penis, hypogonadism, testosterone deficiency, osteoporosis management, aplastic anaemia, endometriosis, angioedema, sports performance enhancement (no longer legal), relief and recovery from common injuries, rehabilitation, weight control, anti-insomnia, and regulation of sexuality, aggression and cognition.

Route
Oral, parenteral.
 
Metabolic effects
Increased protein synthesis and amino acid consumption, androgenesis, catabolism and gluticocototitosis.
 
Adverse effects (men)
Breast enlargement (gynecomastia), testicular atrophy, sterility, sperm abnormalities, impotence, prostatic hypertrophy, myocardial hypertrophy and fibrosis, myocardial infarction and fatal arrhythmias, peliosis hepatis, cholestasis, hepatic adenomas, testicular atrophy, peripheral oedema, intracerebral thrombosis.

Adverse effects (women)
Clitoral hypertrophy, beard growth, baldness, deepened voice, decreased breast size.

Adverse effects (men and women)
Aggression and antisocial behavior, increased risk of cardiovascular disease, peliosis hepatis, haemorrhage, jaundice, acne, accelerated bone maturation resulting in short stature, liver tumours (hepatic adenomas and CA) which may regress with abstinence; AS abusers are at an increased risk for HIV transmission, given the common practice of sharing of needles when injecting ASs.

Lab
ASs are detectable to 1 parts per billion 4 days after last use if the hormone is water-soluble, or 14 days after use in lipid-soluble compounds.

FDA status
ASs are schedule-III drugs per the Controlled Substances Act.

an·a·bol·ic ster·oid

(an'ă-bol'ik ster'oyd)
Prescription drug used in treatment of the anemias and other disorders involving wasting of the body; it has been abused by some athletes to increase muscle mass; functions in a manner similar to that of the chief male hormone, testosterone. Masculinizing effects are minimized by synthetically manipulating chemical structure to emphasize tissue-building, nitrogen-retaining processes.
See also: ergogenic aid
Synonym(s): androgenic steroid.
[G. anabolē, something tossed up, a mound, fr. ana, up + ballein, to throw + steroid]

Anabolic steroid

Drugs, derived from the male sex hormones, which increase the rate of tissue growth. They are best known for increasing the rate of muscle development.
Mentioned in: Antianemia Drugs

an·a·bol·ic ster·oid

(an'ă-bol'ik ster'oyd)
Compound with androgenic properties that increases muscle mass and stimulated protein production; used to treat emaciation; sometimes used by athletes in an effort to increase size, strength, and endurance of muscle. Examples include methyltestosterone, nandrolone, methandrostenolone, and stanozolol.

anabolic

pertaining to or arising from anabolism.

anabolic steroid
steroids with a tissue-building effect. Testosterone is an example of a natural anabolic steroid with the, sometimes undesirable, effect of causing masculinization. Synthetic steroids are designed to avoid this problem as much as possible. The purpose of their use includes improvement in body weight in old animals and in the young after debilitating disease or major surgery.
References in periodicals archive ?
We are thankful as well to other legislators and industry stakeholders who kept the serious issue of designer anabolic steroids in front of key colleagues in Congress.
DASCA will protect consumers as well as responsible companies by empowering the Drug Enforcement Administration (DEA) with new tools to identify and rapidly respond when illegal drugs in the form of new designer anabolic steroids are falsely marketed as dietary supplements.
The charges also involve the alleged possession of Ilium Stanabolic, which contains the anabolic steroid stanozolol.
This study also revealed that 77% of nonmedical anabolic steroid users reported using at least one illicit drug in the past year, including use of prescription drugs for recreational purposes.
Mancini, adding that there's also danger from the side effects of anabolic steroids.
There are two different types of steroids - anabolic steroids that build muscle and corticosteroids that are anti-inflammatory.
But he said the greatest danger is posed by real anabolic steroids, both tablet and liquid form, bought off the internet.
He said that toxicology reports found traces of paracetamol, codeine, amphetamine and anabolic steroids.
In my experience, users often begin with muscle-building supplements and graduate to anabolic steroids when the supplements fail to deliver expected gains in muscle," Green said.
In the gene analysis study being used to attack DHEA, the lead author makes legal conclusions that DHEA should be removed from the OTC (over-the-counter) market and re-classified as an anabolic steroid.
5) Are you aware of any specific reason why athletes 42 48 10 who haven't attained full maturity should avoid anabolic steroid usage?
Anabolic steroids have been used to cheat in professional sport for years.