amyloid angiopathy


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am·y·loid an·gi·op·a·thy

deposition of acellular hyaline material in small arteries and arterioles of the leptomeninges and cerebral cortex in the elderly with resulting predilection for recurrent lobar intraparenchymal hematomas.

amyloid angiopathy

An abnormality of cerebral blood vessels in which amyloid is deposited in the walls of small arteries and arterioles. It may occur in those with chronic infectious and inflammatory disorders or B-cell lymphoma and is a common contributor to intracerebral hemorrhage or Alzheimer's disease in the elderly.
See also: angiopathy
References in periodicals archive ?
Cerebral amyloid angiopathy can also mimic glioma radiologically and clinically.
Does the amyloid angiopathy produce white matter vascular changes?
The patient was elderly; however, no foci of prior hemorrhage were noted, which argued against cerebral amyloid angiopathy.
Cerebral amyloid angiopathy can be differentiated from CADASIL because it presents in older individuals, and staining with Congo red is negative in the latter condition.
CONJUMAB-A has potential application for treatment of several serious diseases, such as Alzheimer's, Parkinson's, Huntington's, Cerebral Amyloid Angiopathy, Frontotemporal Dementia, Progressive Supranuclear Palsy, Pick's disease, Creutzfeldt-Jakob disease and Cortical Basal Degeneration.
Neurochem's research team has been working with international amyloid experts on the development of therapeutic cures to amyloid-related diseases, including Alzheimer's Disease, Secondary Amyloidosis, Diabetes Type II and Hemorrhagic Stroke due to Cerebral Amyloid Angiopathy (CAA).
Previous longitudinal studies of cerebral microbleeds were smaller and focused on patients seen at memory clinics or patients with cerebral amyloid angiopathy instead of the general population.