As with beta-amyloid, the amylin
deposits somehow initiate the process of programmed cell death.
In a separate experiment, the same team gave amylin
injections to 12 healthy rats and noted that their blood glucose rose by 45 percent.
This press release is neither an offer to purchase nor a solicitation of an offer to sell shares of Amylin
Eastbourne believes that shareholders should hold the incumbent Board accountable for the performance of the management it supervises and that the Board has not provided, and as currently composed, will not provide the judgment and strong leadership that Amylin
needs at this critical juncture.
Also yesterday, Bristol-Myers Squibb acquired all of the remaining outstanding shares of Amylin
common stock by means of a "short form merger" in which all such shares, other than shares held by Amylin
in treasury or shares held by Amylin
's stockholders who are entitled to and have properly exercised appraisal rights under Delaware law, were converted into the right to receive $31.
These forward-looking statements include risks and uncertainties that current or future clinical trials will confirm the results referred to in this release or that the multi-dose trial will be completed when planned, risks and uncertainties inherent in the collaboration with and dependence upon Lilly, Amylin
and/or Alkermes; risks and uncertainties regarding the drug discovery and development process, including whether the LAR version of BYETTA will receive regulatory approvals or prove to be commercially successful.
Graham, president and CEO of Amylin
In December of 2002 Curis licensed and assigned patents covering the use of PYY, a peptide made in the gut, to Amylin
Pharmaceuticals for the in vivo treatment of metabolic diseases, including diabetes and obesity.
The agreement provides Amylin
to pay an up-front licensing fee and milestone cash payments based primarily upon obtaining regulatory approval and sales goals from Amylin
Pharmaceuticals to Curis and a royalty on future product sales.
This collaboration with Amylin
, an innovator in the development of next-generation diabetes therapies, confirms our continued commitment to the treatment of diabetes and its complications," said John C.
9, 2010 /PRNewswire-FirstCall/ -- Amylin
Pharmaceuticals is engaged in the discovery, development and commercialization of potential drug candidates for the treatment of diabetes and other metabolic disorders.