amylin


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Related to amylin: Symlin

am·y·lin

(am'i-lin),
A 37-amino acid peptide that is cosecreted with insulin from the pancreatic β-cell. Many of its biologic activities mimic those of calcitonin gene-related peptide, which is not a β-cell peptide. In patients with Type 1 diabetes, amylin is essentially absent from the plasma. The plasma level of amylin rises after a meal or a glucose load.
[amyloid + -in]

amylin

(ăm′ə-lĭn)
n.
1. A peptide hormone that is secreted along with insulin by the beta cells of the pancreas and helps to regulate blood sugar levels by inhibiting glucagon secretion and by slowing the rate at which food leaves the stomach.
2. Archaic Any of various components of starch.

amylin

An older term for:
(1) (Pancreatic) islet amyloid polypeptide;
(2) Amylopectin.

am·y·lin

(am'i-lin)
The cellulose of starch; the insoluble envelope of starch grains.

amylin

see amyloid.
References in periodicals archive ?
As with beta-amyloid, the amylin deposits somehow initiate the process of programmed cell death.
In a separate experiment, the same team gave amylin injections to 12 healthy rats and noted that their blood glucose rose by 45 percent.
This press release is neither an offer to purchase nor a solicitation of an offer to sell shares of Amylin.
Eastbourne believes that shareholders should hold the incumbent Board accountable for the performance of the management it supervises and that the Board has not provided, and as currently composed, will not provide the judgment and strong leadership that Amylin needs at this critical juncture.
Also yesterday, Bristol-Myers Squibb acquired all of the remaining outstanding shares of Amylin common stock by means of a "short form merger" in which all such shares, other than shares held by Amylin in treasury or shares held by Amylin's stockholders who are entitled to and have properly exercised appraisal rights under Delaware law, were converted into the right to receive $31.
These forward-looking statements include risks and uncertainties that current or future clinical trials will confirm the results referred to in this release or that the multi-dose trial will be completed when planned, risks and uncertainties inherent in the collaboration with and dependence upon Lilly, Amylin and/or Alkermes; risks and uncertainties regarding the drug discovery and development process, including whether the LAR version of BYETTA will receive regulatory approvals or prove to be commercially successful.
Graham, president and CEO of Amylin Pharmaceuticals, Inc.
In December of 2002 Curis licensed and assigned patents covering the use of PYY, a peptide made in the gut, to Amylin Pharmaceuticals for the in vivo treatment of metabolic diseases, including diabetes and obesity.
The agreement provides Amylin to pay an up-front licensing fee and milestone cash payments based primarily upon obtaining regulatory approval and sales goals from Amylin Pharmaceuticals to Curis and a royalty on future product sales.
This collaboration with Amylin, an innovator in the development of next-generation diabetes therapies, confirms our continued commitment to the treatment of diabetes and its complications," said John C.
9, 2010 /PRNewswire-FirstCall/ -- Amylin Pharmaceuticals, Inc.
Amylin Pharmaceuticals is engaged in the discovery, development and commercialization of potential drug candidates for the treatment of diabetes and other metabolic disorders.