amplification (redirected from amplified)

amplification /am·pli·fi·ca·tion/ (33000) (am″plĭ-fĭ-ka´shun) the process of making larger, such as the increase of an auditory stimulus, as a means of improving its perception.

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gene amplification  the process by which the number of copies of a gene is increased in certain cells; in humans it is most often seen in malignant cells.

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am·pli·fi·ca·tion (mpl-f-kshn)

n.

1. The process of increasing the magnitude of a variable quantity, especially the magnitude of voltage, power, or current, without altering any other quality.

2. The result of such a process.

3. The process by which genes or DNA sequences are copied in an organism or in the laboratory.

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Amplification

A process by which something is made larger. In clotting, only a very few chemicals are released by the initial injury; they result in a cascade of chemical reactions which produces increasingly larger quantities of different chemicals, resulting in an appropriately-sized, strong fibrin clot.

Mentioned in: Hemophilia

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amplification

[am′plifikā′shən]

Etymology: L, amplificare, to make wider

1 a genetic engineering process in which the amount of plasmid deoxyribonucleic acid (DNA) increases in proportion to the amount of bacterial DNA via treatment with certain substances, including chloramphenicol.

2 the replication in bulk of an entire DNA library. See also polymerase chain reaction. amplify, v.

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amplification

1. the process of making larger, as the increase of an auditory or visual stimulus, as a means of improving its perception.

2. said of a virus means multiplication; replication.

3. in polymerase chain reaction, the synthesis of multiple copies of a particular nucleic acid template sequence.

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amplification

Molecular biology An in vivo–as in the fragile X syndrome or in vitro–as in cloning or PCR ↑ in the number of copies of a specific gene or DNA sequence of interest. See Cloning, DNA amplification, Exon amplification, Extreme amplification, Gene amplification, Linked linear amplification, PCR, PCR amplification of specific alleles, Solid phase amplification.