amplification


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Related to amplification: DNA amplification

amplification

 [am″plĭ-fĭ-ka´shun]
the process of making larger, such as the increase of an auditory or visual stimulus, as a means of improving its perception.
DNA amplification artificial increase in the number of copies of a particular DNA fragment into millions of copies through replication of the segment into which it has been cloned, a type of nucleic acid amplification.
gene amplification a process by which the number of copies of a gene is increased in certain cells because extra copies of DNA are made in response to certain signals of cell development or of stress from the environment. In humans this process is seen most often in malignant cells.
nucleic acid amplification amplification of a specific nucleic acid sequence, such as to test for presence of a given virus or bacteria in a sample. Types include DNA amplification, ligase chain reaction, and polymerase chain reaction.

am·pli·fi·ca·tion

(am'pli-fi-kā'shŭn),
The process of making larger, as in increasing an acoustic or visual stimulus to enhance its perception.
[L. amplificatio, an enlarging]

amplification

/am·pli·fi·ca·tion/ (33000) (am″plĭ-fĭ-ka´shun) the process of making larger, such as the increase of an auditory stimulus, as a means of improving its perception.
gene amplification  the process by which the number of copies of a gene is increased in certain cells; in humans it is most often seen in malignant cells.

amplification

(ăm′plə-fĭ-kā′shən)
n.
1. The act or result of amplifying, enlarging, or extending.
2. Physics
a. The process of increasing the magnitude of a variable quantity, especially the magnitude of voltage, power, or current, without altering any other quality.
b. The result of such a process.
3. Genetics The process by which extra copies of a gene or a DNA sequence are formed.

amplification

[am′plifikā′shən]
Etymology: L, amplificare, to make wider
1 (genetic) a process whereby certain targeted sequences of DNA are replicated by the polymerase chain reaction (PCR) in order to produce multiple copies of a single or limited number of genes. Often this refers to increasing the proportion of plasmid DNA relative to the amount of bacterial DNA.
2 the replication in bulk of an entire DNA library. See also polymerase chain reaction. amplify, v.

amplification

An in vivo (as in the fragile X syndrome) or in vitro (as in cloning or PCR) increase in the number of copies of a specific gene or DNA sequence of interest.

amplification

Molecular biology An in vivo–as in the fragile X syndrome or in vitro–as in cloning or PCR ↑ in the number of copies of a specific gene or DNA sequence of interest. See Cloning, DNA amplification, Exon amplification, Extreme amplification, Gene amplification, Linked linear amplification, PCR, PCR amplification of specific alleles, Solid phase amplification.

am·pli·fi·ca·tion

(am'pli-fi-kā'shŭn)
1. The process of making larger, as in increasing an auditory or visual stimulus to enhance its perception.
2. molecular biology Process of increasing the number of nucleic acid copies in a sample to millions within a short period.
[L. amplificatio, an enlarging]

amplification

The production of extra copies of a DNA sequence. These may be within the chromosomal sequence or outside it.

Amplification

A process by which something is made larger. In clotting, only a very few chemicals are released by the initial injury; they result in a cascade of chemical reactions which produces increasingly larger quantities of different chemicals, resulting in an appropriately-sized, strong fibrin clot.
Mentioned in: Hemophilia

amplification

1. the process of making larger, as the increase of an auditory or visual stimulus, as a means of improving its perception.
2. said of a virus means multiplication; replication.
3. in polymerase chain reaction, the synthesis of multiple copies of a particular nucleic acid template sequence.
References in periodicals archive ?
Amplification efficiency was calculated based on the delta Ct between nonamplified cDNA targets and amplified cDNA, with added consideration of dilution factors, given the relative differences in cDNA concentration.
Anti-brevetoxins antibodies at increasing dilution incubated in wells of the sensitized plates were successful in quantitative detection using all three signal amplification procedures described in "Materials and Methods.
The achievement of matter-wave amplification suggests that atom optics might one day prove as rich and rewarding as recent developments using conventional lasers that beam photons.
Conduct a massive in-house chart review, including review of case histories, to identify all residents in need of amplification
Once it has been determined that an older person is a candidate for hearing aid use, careful consideration must then be given to several factors in selecting an appropriate amplification device.
The Amplifluor technology is compatible with all primer-based amplification systems, including polymerase chain reaction.
Gene amplification technology plays a vital role in the diagnostics field.
Available Types of Gene Amplification Technologies II-3
In a series of articles, we have demonstrated that a specific sequence of hydrologic conditions, spring drought followed by continued summer rainfall, is critical for the amplification and transmission of both SLEV and WNV in south Florida (31,35-38).
With chirped pulse amplification, saysMourou, "we can use a system that is 1,000 times smaller.
This Dashboard reveals key market indicators for the nucleic acid amplification market as a whole as well as for the following sub-segments: Standard PCR with Taq polymerase, hot start Taq polymerase and proofreading polymerases
Use of Nucleic Acid Sequence-Based Amplification for