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An acid-stable semisynthetic penicillin derived from 6-aminopenicillanic acid; it has a broader spectrum of antimicrobial action than penicillin G, inhibits the growth of gram-positive and gram-negative bacteria, and is not resistant to penicillinase; also available as ampicillin sodium and ampicillin trihydrate.
ampicillin/am·pi·cil·lin/ (am″pĭ-sil´in) a semisynthetic, acid-resistant, penicillinase-sensitive penicillin used as an antibacterial against many gram-negative and gram-positive bacteria; also used as the sodium salt.
A broad-spectrum semisynthetic penicillin, C16H19N3O4S, that is used, often in the form of its sodium salt, to treat infections of the intestinal, urinary, and respiratory tracts.
a semisynthetic aminopenicillin.
indication It is prescribed in the treatment of infections caused by a broad spectrum of sensitive gram-negative and gram-positive organisms.
contraindication Known hypersensitivity to any penicillin prohibits its use.
adverse effects Among the most serious adverse reactions are anaphylaxis, nausea, and diarrhea. Fever, rashes, allergic reactions, and suprainfection also may occur.
ampicillinInfectious disease An analogue of penicillin, which inhibits crosslinking of peptidoglycan chains in the eubacterial cell wall. Ampicillin is comparable to penicillin G against gram-positive bacteria, but more active against gram-negative bacilli Adverse effects Rash, especially if Pt also receiving allopurinol or actively infected with EBV
ampicillinA widely used penicillin antibiotic, effective by mouth and capable of killing many GRAM-NEGATIVE as well as GRAM-POSITIVE organisms. About one third of the dose is excreted unchanged in the urine. The drug precipitates a characteristic rash if given to people incubating GLANDULAR FEVER (infective mononucleosis). The drug is on the WHO official list. A brand name is Penbritin.
An acid-stable semi-synthetic penicillin that inhibits the growth of gram-positive and gram-negative bacteria and is not resistant to penicillinase.
an aminopenicillin of synthetic origin, susceptible to β-lactamase, with activity similar to amoxicillin but shorter duration of activity. It can be administered orally or parenterally.